LAISHA · DRAVYAGUNA

Guduchi

गुडूची

Tinospora cordifolia (Willd.) Hook.f. & Thomson

Menispermaceae · Tinospora

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Giloy

What the texts say Guduchi does

What the evidence says. Traditional use is extensive and long recorded. Modern clinical evidence is limited.

Side effects and limits

Avoid or ask first: Autoimmune conditions — caution is advised, and a practitioner should be asked first.; Existing liver disease — caution is advised in light of the reported cases above.

A traditional classification, not a recommendation. The full safety record is below.

Stands in 15 groups

A Samhita can only be read forwards, from the group to its members. This is the same list read backwards.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Churna3–6 g
Swarasa10–20 ml
Kwatha50–100 ml
Satva1–3 g
AnupanaUshnodaka · Madhu · Ghrita
KalaAdhobhakta

Satva (the starch) is a distinct preparation with its own matra and is the sheeta form.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Pharmacopoeial standard

Ayurvedic Pharmacopoeia of India, Part I

MarkerStarch (satva) content and TLC identity
AssayAs the monograph gives
Total ashTotal ash not more than 16 per cent
Acid-insoluble ashNot more than 3 per cent
Alcohol-soluble extractiveAlcohol-soluble extractive not less than 3 per cent
Water-soluble extractiveWater-soluble extractive not less than 11 per cent
Foreign matterForeign matter not more than 2 per cent

Stem only. A high acid-insoluble ash points to adhering soil, and to stem collected from the ground rather than climbing.

These are the pharmacopoeial limits for the article, not a test Laisha has run on anything. They are here so a practitioner can ask a supplier for a certificate of analysis and know what the numbers on it should say.

Rasapanchaka

Rasa
TiktaKashaya
Guna
LaghuSnigdha
ViryaUshna
VipakaMadhura
PrabhavaClassified as rasayana. Charaka's Sutrasthana groups it among the dravya that act on fever, and the texts treat its rasayana action as prabhava rather than as a consequence of its rasapanchaka.
DoshakarmaTridoshahara. A tikta dravya with ushna virya and madhura vipaka is an unusual combination, and it is that combination the texts credit for its action on all three doshas.

Tikta predominant, with kashaya. It is among the dravya where the vipaka differs strikingly from the rasa, and that contrast is the usual examination point.

Karma and part used

RasayanaDeepanaBalyaJvaraharaTrishnaharaDahaprashamana

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaKanda (the mature stem)
Why it mattersThe mature stem is the dravya. The classical texts and the pharmacopoeia both specify the stem, and the leaf is not a substitute for it. Stem collected from a plant growing on a neem tree is traditionally held to be superior, which is a statement about the tradition rather than a tested claim.

Paryaya

AmritaMadhuparniChhinnaruhaVatsadaniJivantika

Amrita means nectar or the undying, and Chhinnaruha means one that grows again after being cut — a name describing the plant's habit, which is how a student is expected to recognise it.

Names, by language

EnglishHeart-leaved moonseed
SinhalaRasakinda
NepaliGurjo
HindiGiloy
KannadaAmruthaballi
TamilSeendhil
TeluguTippateega
MalayalamChittamruthu
MarathiGulvel
GujaratiGalo
BengaliGulancha
PunjabiGilo
OdiaGuluchi
UrduGilo

Classical references

Charaka Samhita
Sutrasthana, chapter 4 (Shadvirechanashatashritiya)
Groups guduchi among the dravya listed by their action.
Charaka Samhita
Chikitsasthana, chapter 1 (Rasayana)
Guduchi appears among the rasayana dravya.
Bhavaprakasha Nighantu
Guduchyadi Varga, the opening dravya
The varga is named after guduchi; gives its rasa, guna, virya and vipaka.
Sushruta Samhita
Sutrasthana, chapter 38 (Dravyasangrahaniya)
Includes guduchi in the groups of dravya arranged by action.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check. Where an exact chapter and verse could not be confirmed, this library names the section rather than inventing a number.

Formulations it appears in

Guduchi SatvaThe starch settled out of the fresh stem; a preparation named for the dravya.
AmritarishtaNamed for guduchi's own synonym, Amrita.
Guduchyadi KashayaGuduchi is the named principal dravya.
ChyawanprashPresent among the many dravya of the formulation.

Adulterants and substitutes

Tinospora sinensis is collected and sold alongside it, particularly as dried stem where the two are hard to tell apart. Stems of unrelated climbers are also sold as giloy in loose markets. Once cut and dried the distinguishing features are largely gone, which is the argument for buying from a source that can say where it was collected.

Identity

Matched live against the GBIF backbone on 28 September 2026 at 97 per cent confidence. The name most often confused with it is Tinospora sinensis, a real and separate species sold under the same vernacular names in several markets; the two are not treated as interchangeable by the pharmacopoeia.

A WAY TO REMEMBER IT

Tinospora is teinos (stretched) + spora (seed). Cordifolia is heart-leaved. The heart-shaped leaf is the field mark; cordifolia tells you so.

What the tradition holds

Guduchi is classed among the rasayana dravya and the Bhavaprakasha Nighantu names a whole varga after it. Ayurveda records it as acting on all three doshas and describes a jvarahara action. That is what the tradition holds and where it is written down, not a finding about what the stem does in a body.

Constituents. The stem carries a range of alkaloids, diterpenoid lactones, glycosides and a starch fraction that is settled out separately as Guduchi Satva. Composition varies with the season of collection and with what the plant was climbing on.

What the evidence says

StatusTraditional use is extensive and long recorded. Modern clinical evidence is limited.
SuggestedHealth Canada publishes monographs covering Ayurvedic ingredients and permits specific traditional-use claims, which reflects a regulator accepting a documented tradition rather than a body of clinical trial evidence.
Not establishedThere is not enough good clinical evidence to establish an effect on any named health condition. Long traditional use is not a substitute for that evidence, and this library does not present it as one.
The honest gapPublished work rarely records which Tinospora species was used or the season of collection, and both change the material. Two papers on guduchi may not be papers on the same thing.

Safety

Reports of liver injury associated with giloy products appeared in India during and after 2021, and while species misidentification and adulteration were proposed as explanations rather than the plant itself, the reports are real and are the reason this entry does not treat it as harmless. Anyone with liver disease, on medication, pregnant, or managing an autoimmune condition should speak to a doctor or a qualified practitioner before taking it.

Side effectsDigestive discomfort
ContraindicationsAutoimmune conditions — caution is advised, and a practitioner should be asked first.
Existing liver disease — caution is advised in light of the reported cases above.
InteractionsImmunosuppressants, including after transplant — guduchi is used as an immunomodulator and the direction of effect opposes them.
Antidiabetic medicines — a hypoglycaemic effect is reported; monitor rather than assume.
A hepatotoxicity signal was reported in India in 2020–21, with a series of autoimmune-like hepatitis cases attributed to Tinospora. Misidentification with Tinospora crispa, which is hepatotoxic, is one proposed explanation and is a reason to be certain of the species and the supplier. Stop and investigate if transaminases rise.
Pregnancy and breastfeedingThere is not enough evidence to establish safety in pregnancy or breastfeeding, and a qualified practitioner should be asked first.
Reported liver injuryCase reports of hepatic injury associated with giloy preparations were published from India from 2021 onward. Whether the cause was the plant, a misidentified Tinospora species, or an adulterant remains unsettled in the literature. Unsettled is not the same as disproved, and this entry states it rather than leaving it out.

Growing it

ClimateTropical and subtropical; grows through most of the Indian subcontinent as a climber on other trees.
SoilUndemanding, drained.
PlantingGrown from stem cuttings, which root readily. Needs a host tree or a support to climb.
HarvestMature stem is cut, traditionally in the cooler months. The plant regrows from what is left, which is the habit its name Chhinnaruha describes.
What is not statedThis library has not verified region-specific spacing, variety and yield figures against a named agricultural authority for every growing country, and does not state them rather than guessing.

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What this is not

Sources

GBIF Backbone Taxonomy species-match record for Tinospora cordifolia (Willd.) Hook.f. & Thomson
Global Biodiversity Information Facility (GBIF) · read 2026-09-28
Confirming live, rather than from memory, the accepted botanical name and family behind the Sanskrit name.
https://api.gbif.org/v1/species/match?name=Tinospora%20cordifolia
The Ayurvedic Pharmacopoeia of India — Guduchi (Tinospora cordifolia)
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-28
The official Indian pharmacopoeial standing of the dravya and the identity of the part used as the pharmacopoeial article.
https://pcimh.gov.in/
Compendium of Monographs — Natural Health Products
Health Canada, Natural and Non-prescription Health Products Directorate · read 2026-09-28
A regulator outside India that publishes monographs covering Ayurvedic ingredients — used for the safety framing, and for the line between a permitted traditional-use claim and clinical evidence.
https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/applications-submissions/product-licensing/compendium-monographs.html
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it. Sharangadhara is where Ayurveda's dose forms and their measures are set out, and it is what every Dravyaguna textbook reproduces.
https://niimh.nic.in/ebooks/esharangadhara/
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