LAISHA · DRAVYAGUNA

Karavira

करवीर

Nerium oleander L.

Apocynaceae · Nerium

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Kaner

What the texts say Karavira does

What the evidence says. Traditional use is extensive and long recorded. Modern clinical evidence is limited.

Side effects and limits

Avoid or ask first: Internal use of any kind, by anyone, in any quantity.; Self-treatment, absolutely.; Pregnancy and breastfeeding.; and more below.

A traditional classification, not a recommendation. The full safety record is below.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Shodhita mula twak30–125 mg, specialist use only
AnupanaGhrita

Oleandrin is a cardiac glycoside. Every part is poisonous. Internal use only within a classical yoga after shodhana.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Rasapanchaka

Rasa
KatuTiktaKashaya
Guna
LaghuRukshaTikshna
ViryaUshna
VipakaKatu
PrabhavaThe texts use karavira externally for obstinate skin disease and for wounds where nothing gentler will serve, and class it firmly among the poisons.
DoshakarmaKaphavatahara.

Katu, tikta and kashaya with ushna virya and katu vipaka.

Karma and part used

KushthaghnaKrimighnaVranashodhanaVishaghna

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaMula (the root), externally and only after shodhana
Why it mattersThe root is the article, used externally and only after purification. Every part of this plant is poisonous, including the flowers, the leaves and the smoke from burning it.

Paryaya

AshvamarakaHayamarakaShatakumbhaVirakaPratihasa

Ashvamaraka and Hayamaraka both mean horse-killer. The tradition named this plant for what it does to a large animal that eats it, and a student should never need a second reminder.

Names, by language

EnglishOleander
SinhalaKaneru
NepaliKarbir
HindiKaner
KannadaKanagile
TamilArali
TeluguGanneru
MalayalamArali
MarathiKanher
GujaratiKaren
BengaliKarabi
PunjabiKaner
OdiaKarabira
UrduKaner

Classical references

Sushruta Samhita
Kalpasthana, the chapters on poisons
Karavira is described among the sthavara visha with the signs of poisoning by it.
Bhavaprakasha Nighantu
Guduchyadi Varga
Gives the rasa, guna, virya and vipaka of karavira and names it among the poisons.
Rasatarangini
The chapter on visha dravya
Gives the shodhana procedure for karavira before any use.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check. Where an exact chapter and verse could not be confirmed, this library names the section rather than inventing a number.

Formulations it appears in

Karavira TailaAn oil named for the dravya, used externally only.
Vishagarbha TailaPurified karavira is among the dravya, for external use.

Adulterants and substitutes

Nerium oleander and the yellow oleander, Cascabela thevetia, are both called Kaner in Indian markets and both are deadly, with different glycosides. That two poisons share a common name is the substitution problem here, and it matters because the poisoning picture and the treatment differ.

Identity

Matched live against the GBIF backbone on 28 September 2026 at 99 per cent confidence. Classed among the sthavara visha, the poisons of plant origin, and among the upavisha. The two answer different questions: sthavara visha is the ORIGIN, against jangama visha of animal origin; upavisha is the GRADE in Rasashastra, the lesser poisons usable after shodhana, against the mahavisha. Planted as an ornamental on roadsides and in gardens across India, which is precisely what makes it dangerous — it is the most accessible deadly plant most people will ever walk past.

A WAY TO REMEMBER IT

Nerium is neros, water — it grows along streams. Oleander is olea (olive) + dendron (tree), for the leaf shape. Kara-vira means the one that kills the hero: entirely poisonous.

What the tradition holds

Karavira is described in the Sushruta Samhita among the plant poisons and in the Bhavaprakasha Nighantu. That is what the tradition holds and where it is written down, not a finding about what the root does in a body.

Constituents. Every part carries cardiac glycosides, chiefly oleandrin, which act on the heart in the same way digoxin does.

What the evidence says

StatusTraditional use is extensive and long recorded. Modern clinical evidence is limited.
SuggestedNo claim of established clinical effect is made here. The modern literature on this plant is almost entirely about poisoning and about suicide.
Not establishedThere is not enough good clinical evidence to establish an effect on any named health condition. Long traditional use is not a substitute for that evidence, and this library does not present it as one.
The honest gapGlycoside content varies by part and season and is not knowable without assay.

Safety

This plant kills people and is one of the commonest causes of fatal plant poisoning in India. A very small quantity of leaf — a few leaves, and reports exist of one — can kill an adult through heart rhythm failure. Children have died from chewing flowers. Honey from its nectar has caused poisoning, and so has smoke from burning the wood and water in which cuttings stood. It is used in Ayurveda externally, after shodhana, and never internally by anyone reading this. Nothing here is a preparation to attempt. Suspected oleander poisoning is a hospital emergency, and digoxin-specific antibody treatment exists — reaching a hospital is the response, not a remedy.

Side effectsSevere skin irritation on contact
Nausea and vomiting — in this plant an early sign of poisoning, not a side effect
ContraindicationsInternal use of any kind, by anyone, in any quantity.
Self-treatment, absolutely.
Pregnancy and breastfeeding.
Children — including having the plant where a child can reach it.
InteractionsOleandrin is a cardiac glycoside. With digoxin the toxicity is additive and the drug level will not show it.
Any potassium-losing drug — diuretics, corticosteroids — increases glycoside toxicity.
Every part of the plant is poisonous. Internal use only within a classical formulation after shodhana.
Pregnancy and breastfeedingNot to be used in pregnancy or breastfeeding in any quantity or form.
A small quantity of any part can killOleandrin and related cardiac glycosides are present throughout the plant. A few leaves can kill an adult through ventricular arrhythmia; children have died after chewing flowers. It is among the leading causes of fatal plant poisoning in India, both accidental and deliberate.
Poisoning by routes people do not expectCases are recorded from honey made from its nectar, from smoke when the wood is burnt, and from water in which cuttings had stood. Avoiding the leaves is not the whole of avoiding the plant.

Growing it

ClimateTropical and subtropical; extremely drought-hardy.
SoilAlmost any, including poor and saline ground.
PlantingGrown from cuttings and planted widely as an ornamental — which is the reason so many poisonings happen.
HarvestRoots are taken with protection and are a poison from the moment they leave the ground.
What is not statedThis library has not verified region-specific spacing, variety and yield figures against a named agricultural authority for every growing country, and does not state them rather than guessing.

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What this is not

Sources

GBIF Backbone Taxonomy species-match record for Nerium oleander L.
Global Biodiversity Information Facility (GBIF) · read 2026-09-28
Confirming live, rather than from memory, the accepted botanical name and family behind the Sanskrit name.
https://api.gbif.org/v1/species/match?name=Nerium%20oleander
The Ayurvedic Pharmacopoeia of India — Karavira (Nerium oleander L.)
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-28
The official Indian pharmacopoeial standing of the dravya and the identity of the part used as the pharmacopoeial article.
https://pcimh.gov.in/
Compendium of Monographs — Natural Health Products
Health Canada, Natural and Non-prescription Health Products Directorate · read 2026-09-28
A regulator outside India that publishes monographs covering Ayurvedic ingredients — used for the safety framing, and for the line between a permitted traditional-use claim and clinical evidence.
https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/applications-submissions/product-licensing/compendium-monographs.html
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it. Sharangadhara is where Ayurveda's dose forms and their measures are set out, and it is what every Dravyaguna textbook reproduces.
https://niimh.nic.in/ebooks/esharangadhara/
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