LAISHA · DRAVYAGUNA

Madanaphala

मदनफल

Catunaregam spinosa (Thunb.) Tirveng.

Rubiaceae · Catunaregam

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Mainphal

What the texts say Madanaphala does

What the evidence says. Traditional use is long recorded. Modern clinical evidence is limited.

Side effects and limits

Avoid or ask first: Not used outside a supervised vamana procedure.; Not used in the very young, the very old, the debilitated, or in those with cardiac or respiratory disease, following the classical list of ayogya for vamana.

A traditional classification, not a recommendation. The full safety record is below.

Stands in 4 groups

A Samhita can only be read forwards, from the group to its members. This is the same list read backwards.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Churna for vamana4–8 g, within a supervised procedure
AnupanaMadhu · Saindhava · Ushnodaka
KalaAs the vamana procedure directs

A quantity for a supervised vamana conducted by a practitioner, never a dose to be taken by anyone on their own.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Rasapanchaka

Rasa
MadhuraTiktaKashaya
Guna
LaghuRukshaTikshna
ViryaUshna
VipakaKatu
PrabhavaMadanaphala is called the foremost of all vamaka dravya, and Charaka states that it does not harm even when it fails to act, which is why it heads the group.
DoshakarmaKaphavatahara.

Madhura, tikta and kashaya with ushna virya and katu vipaka. It is the rare instance where the rasa gives almost no clue to the action, which the texts attribute to prabhava.

Karma and part used

VamakaLekhanaShothaharaVrana shodhanaKrimighna

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaPhala (the dried fruit)
Why it mattersThe dried fruit, and its pulp. It is the article for vamana and the seed is not used separately.

Paryaya

MadanaPindiChhardanaVishapushpakaKarahata

Chhardana names the action directly - that which causes vomiting. The texts rarely leave the chief vamaka drug ambiguous.

Names, by language

EnglishEmetic nut
HindiMainphal
KannadaKarehannu
TamilMarukkarai
TeluguManga
MalayalamMalankara
MarathiGela
GujaratiMindhal
BengaliMayaphal
OdiaMainaphala
UrduMainphal

Classical references

Charaka Samhita
Kalpasthana, chapter 1 (Madanakalpa)
The whole first chapter of the Kalpasthana is given to Madanaphala, and it is named the best of the emetic drugs.
Sushruta Samhita
Sutrasthana, chapter 38 (Dravyasangrahaniya)
Named as Madana in the Aragvadhadi and Mushkakadi ganas.
Bhavaprakasha Nighantu
Guduchyadi Varga
Gives the rasa, guna, virya and vipaka.

Formulations it appears in

Madanaphala Pippali YogaNamed for the dravya, the standard vamana preparation.
Vamana YogaThe principal dravya of the classical emetic combinations.
Madanaphaladi KwathaNamed for the dravya.

Adulterants and substitutes

The fruits of several Rubiaceae are sold as mainphal, and old stock is the commoner problem: the emetic activity falls with storage, so a sample that is genuine but aged simply does not act. Charaka's instruction to collect it in a particular season and store it in a particular way is about potency, not ritual.

Identity

Long published as Randia dumetorum, which is the name most Indian textbooks still use. Catunaregam spinosa is the accepted name in the current backbone and both refer to the same plant.

A WAY TO REMEMBER IT

Catunaregam is from the Malayalam katuna regam. Spinosa, for the thorns. Madana means intoxicating or maddening; the fruit was also used to stupefy fish, which is the same property read from the other end.

What the tradition holds

Charaka gives the first chapter of the whole Kalpasthana to Madanaphala and names it the foremost of the vamaka dravya. That is what the tradition records and where it is set down.

What the evidence says

StatusTraditional use is long recorded. Modern clinical evidence is limited.
SuggestedThe dravya holds a pharmacopoeial monograph in India, which records an accepted identity and quality standard for the article. That is a standard for the material, not evidence of an effect in a body.
Not establishedThere is not enough good clinical evidence to establish an effect on any named health condition. Long traditional use is not a substitute for that evidence, and this library does not present it as one.
The honest gapPublished work on this dravya rarely records the origin or the standard of the material tested, so results cannot be attributed to a defined article.

Safety

This is the principal emetic drug of Ayurveda and it works. Vamana is a supervised procedure with defined preparation, defined endpoints and defined complications, and this dravya is not something to take outside it. Charaka's remark that it does not harm even when it fails to act refers to its use within a properly conducted vamana, not to casual use. Anyone pregnant, on medication or managing a diagnosed condition should speak to a doctor or a qualified practitioner first.

Side effectsVomiting, which is the intended action
Weakness and thirst after the procedure
ContraindicationsNot used outside a supervised vamana procedure.
Not used in the very young, the very old, the debilitated, or in those with cardiac or respiratory disease, following the classical list of ayogya for vamana.
InteractionsNo specific drug interaction is documented for this dravya. That is the honest state of the evidence, not a statement that none exists — most Ayurvedic dravya have never been studied for interaction with modern medicines at all.
Pregnancy and breastfeedingNot used in pregnancy. Vamana is classically contraindicated in pregnancy and an emetic drug has no place there.

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What this is not

Sources

GBIF Backbone Taxonomy species-match record for Catunaregam spinosa (Thunb.) Tirveng.
Global Biodiversity Information Facility (GBIF) · read 2026-09-29
The accepted botanical name and family standing behind the Sanskrit name.
https://api.gbif.org/v1/species/match?name=Catunaregam%20spinosa
The Ayurvedic Pharmacopoeia of India, Part I
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-29
The official Indian pharmacopoeial standing of the dravya and which part is the pharmacopoeial article.
https://pcimh.gov.in/
Bhavaprakasha Nighantu
Bhavaprakasha Nighantu · read 2026-09-29
The rasa, guna, virya and vipaka as the nighantu gives them.
https://niimh.nic.in/ebooks/ebnighantu/
Sharangadhara Samhita, Madhyama Khanda — the matra of the kalpanas
Sharangadhara Samhita, Madhyama Khanda · read 2026-09-29
The classical quantity for each preparation, cited to where the number comes from.
https://niimh.nic.in/ebooks/esharangadhara/
← all dravya