LAISHA · DRAVYAGUNA

Manahshila

मनःशिला

Arsenic disulphide, As2S2 (also written As4S4). A red arsenic mineral.

Parthiva · mineral origin · Uparasa

SHODHANA — NO MINERAL DRAVYA IS USED RAW

Boiled in ardraka swarasa or in agastya patra swarasa by the dola yantra method, repeatedly. As with haratala, this changes the form and removes gross impurity; the arsenic remains.

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Mainsil

What the texts say Manahshila does

What the evidence says. Toxicological literature is substantial for realgar across both Ayurveda and traditional Chinese medicine. Efficacy evidence for the classical preparations is not established.

Side effects and limits

This is arsenic, as haratala is. Realgar is used in traditional Chinese medicine as well and arsenic poisoning from both traditions is documented. Realgar converts to more soluble and more toxic arsenic species on exposure to light and air over time, which is a storage problem specific to this mineral.

Avoid or ask first: Pregnancy and breastfeeding.; Children.; Renal or hepatic impairment.; and more below.

A traditional classification, not a recommendation. The full safety record is below.

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Shuddha15–30 mg, within a yoga, specialist use only
AnupanaMadhu · Ghrita

Never given alone. It appears in named yogas — Shwasa Kuthara rasa among them — prepared by a qualified practitioner.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Rasapanchaka

Rasa
KatuTikta
Guna
SnigdhaGuru
ViryaUshna
VipakaKatu
DoshakarmaKaphavatahara. Aggravates pitta.

Karma and part used

KushthaghnaKrimighnaShwasaharaVishaghna
Upayukta angaShuddha manahshila, and only within a yoga

Paryaya

ManognaNaganamikaShilarasa

Manahshila is classed among the Uparasa.

Names, by language

EnglishRealgar, red arsenic
HindiMainsil
KannadaManashile

Classical references

Rasa Ratna Samuccaya
Chapter 3
Places manahshila among the uparasa and gives its varieties and shodhana.
Rasa Tarangini
Taranga 11
Gives the shodhana and the consequences of unpurified use.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check.

Adulterants and substitutes

Constantly confused with Haratala. Manahshila is the RED disulphide; Haratala is the yellow trisulphide. Both are arsenic and a shop will supply either under either name.

Identity

Arsenic disulphide, As2S2 (also written As4S4). A red arsenic mineral.

A WAY TO REMEMBER IT

Manah-shila is mind-stone. Realgar is from the Arabic rahj al-ghar, powder of the mine.

What the tradition holds

Manahshila is an uparasa used in classical yogas for shwasa and kasa. As with haratala the texts class it as a poison requiring shodhana.

Constituents. Arsenic disulphide, As2S2 (also written As4S4). A red arsenic mineral.

What the evidence says

StatusToxicological literature is substantial for realgar across both Ayurveda and traditional Chinese medicine. Efficacy evidence for the classical preparations is not established.
The honest gapMineral and animal dravya are far less studied than plant dravya, and what study exists is chiefly characterisation and toxicology rather than clinical efficacy.

Safety

This is arsenic, as haratala is. Realgar is used in traditional Chinese medicine as well and arsenic poisoning from both traditions is documented. Realgar converts to more soluble and more toxic arsenic species on exposure to light and air over time, which is a storage problem specific to this mineral.

ContraindicationsPregnancy and breastfeeding.
Children.
Renal or hepatic impairment.
Any use outside a qualified Rasashastra practitioner's hands.
InteractionsAny drug prolonging the QT interval.
Chelating agents — the treatment for arsenic toxicity.
Any nephrotoxic or hepatotoxic drug — additive burden.
Pregnancy and breastfeedingAbsolutely contraindicated.

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What this is not

Sources

Rasa Ratna Samuccaya and Rasa Tarangini
National Institute of Indian Medical Heritage
The classical Rasashastra position: which group the dravya belongs to, its shodhana and marana, and the matra of the prepared form.
https://niimh.nic.in/ebooks/
Ayurvedic Pharmacopoeia of India
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India
The official Indian pharmacopoeial standing of the dravya and the identity of the prepared article.
https://pcimh.gov.in/
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it.
https://niimh.nic.in/ebooks/esharangadhara/
Lead, mercury and arsenic in Ayurvedic medications
Centers for Disease Control and Prevention (CDC)
The documented poisonings from Ayurvedic preparations containing heavy metals, reported by a health authority outside India, and the reason this entry states the hazard alongside the tradition.
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5326a3.htm
Toxicological profile
Agency for Toxic Substances and Disease Registry (ATSDR)
The toxicology of the element itself — route, accumulation, target organ and the exposure at which harm is documented.
https://www.atsdr.cdc.gov/toxprofiledocs/index.html
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