LAISHA · DRAVYAGUNA

Nimba

निम्ब

Azadirachta indica A.Juss.

Meliaceae · Azadirachta

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Neem

What the texts say Nimba does

What the evidence says. Not established for any internal health purpose, and the safety signal is far stronger than any benefit signal.

Side effects and limits

Avoid or ask first: Never give neem oil by mouth to an infant or young child.; Do not take neem oil internally at any age.

A traditional classification, not a recommendation. The full safety record is below.

Stands in 8 groups

A Samhita can only be read forwards, from the group to its members. This is the same list read backwards.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Churna2–4 g
Kwatha50–100 ml
Patra swarasa5–10 ml
AnupanaUshnodaka · Madhu
KalaAdhobhakta

Neem oil is NOT interchangeable with these and is the form implicated in paediatric poisoning. Never give the oil to an infant.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Pharmacopoeial standard

Ayurvedic Pharmacopoeia of India, Part I

MarkerNimbin and azadirachtin on TLC
AssayAs the monograph gives
Total ashTotal ash not more than 12 per cent
Acid-insoluble ashNot more than 2 per cent
Alcohol-soluble extractiveAlcohol-soluble extractive not less than 4 per cent
Water-soluble extractiveWater-soluble extractive not less than 10 per cent
Foreign matterForeign matter not more than 2 per cent

Melia azedarach — the bakain — is substituted for Azadirachta indica and is more toxic. The TLC separates them.

These are the pharmacopoeial limits for the article, not a test Laisha has run on anything. They are here so a practitioner can ask a supplier for a certificate of analysis and know what the numbers on it should say.

Rasapanchaka

Rasa
TiktaKashaya
Guna
LaghuRuksha
ViryaSheeta
VipakaKatu
PrabhavaThe texts group nimba among the kandughna and krimighna dravya.
DoshakarmaKaphapittahara. Being ruksha and sheeta it can increase vata, which the texts note.

Tikta predominant. It is the dravya most often given as the example of tikta rasa itself.

Karma and part used

KrimighnaKandughnaKushthaghnaJvaraharaVishaghna

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaPatra (leaf)
Twak (bark)
Phala (fruit)
Taila (seed oil)
Why it mattersThese are not interchangeable, and the difference is the most important thing on this page. Neem leaf and neem seed oil have very different safety records, and most of the documented harm involves the oil.

Paryaya

ArishtaPichumardaSarvatobhadraTiktaPrabhadra

Arishta means that which keeps off harm. Pichumarda names a use. The paryaya carry the reputation, not the pharmacology.

Names, by language

EnglishNeem
SinhalaKohomba
NepaliNeem
ArabicNeem
HindiNeem
KannadaBevu
TamilVembu
TeluguVepa
MalayalamAryaveppu
MarathiKadunimb
GujaratiLimdo
BengaliNim
PunjabiNimm
OdiaNimba
UrduNeem

Classical references

Charaka Samhita
Sutrasthana, chapter 4 (Shadvirechanashatashritiya)
Places nimba among the kandughna dravya.
Bhavaprakasha Nighantu
Guduchyadi Varga
Gives the rasa, guna, virya and vipaka of nimba.
Sushruta Samhita
Sutrasthana, chapter 38 (Dravyasangrahaniya)
Included among the dravya grouped by action.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check. Where an exact chapter and verse could not be confirmed, this library names the section rather than inventing a number.

Formulations it appears in

Nimbadi ChurnaNamed for the dravya.
Panchanimba ChurnaBuilt on five parts of the neem tree.
Nimba TailaThe seed oil, used externally.

Adulterants and substitutes

Melia azedarach, the bakain or Persian lilac, is a different tree that looks similar, grows alongside neem and is repeatedly sold as it. That substitution matters more than most: Melia azedarach is documented as toxic. Leaf shape distinguishes them on the tree and nothing distinguishes them in a powder.

Identity

Matched to the accepted name in the GBIF backbone at 99% confidence. The author abbreviation A.Juss. is Adrien-Henri de Jussieu, who described the species.

A WAY TO REMEMBER IT

Azadirachta is from Persian azad-dirakht, the free or noble tree. Indica, of India. The Persian name is inside the Latin.

What the tradition holds

Neem has a long place in Ayurveda as nimba, and the leaf, bark and oil have each been used differently. Neem twigs are widely used for cleaning teeth, and the oil is applied externally in traditional practice. That is what the tradition holds; it is not a finding about what the plant does in a body, and tradition is not a safety record — the oral toxicity in children described above occurred within traditional use.

What the evidence says

StatusNot established for any internal health purpose, and the safety signal is far stronger than any benefit signal.
SuggestedNeem is studied in dermatology and as an agricultural pest deterrent, where azadirachtin is the active compound. Laisha does not hold a sourced clinical finding for any internal human use and states none.
Not establishedNo internal medicinal use of neem is established here. Where a plant's documented harm is better characterised than its documented benefit, that asymmetry is the finding.
The honest gapMost of the reliable literature on neem in humans is case reports of poisoning rather than trials of benefit. That is an honest description of the evidence base, not a criticism of the plant.

Safety

Neem oil is dangerous to infants and young children taken by mouth, and has killed. Adults have also developed toxic encephalopathy after ingesting neem oil. External and dental traditional uses have a different record from swallowing the oil, and the two should never be reasoned about together.

Side effectsVomiting, often within minutes of ingestion
Drowsiness progressing to altered consciousness
Rapid breathing
Diarrhoea
ContraindicationsNever give neem oil by mouth to an infant or young child.
Do not take neem oil internally at any age.
InteractionsAntidiabetic medicines — a hypoglycaemic effect is documented for the leaf.
Immunosuppressants — immunostimulant direction opposes them.
Neem OIL in infants and small children has caused a Reye-like encephalopathy with fatty liver, documented in paediatric series. This is an absolute contraindication, not a caution, and it is the oil specifically.
Pregnancy and breastfeedingLaisha holds no sourced safety position for neem in pregnancy or breastfeeding, and offers none. Given the documented toxicity of the oil, this is a question for a doctor rather than for a page.
Toxic encephalopathy and Reye-like syndrome in infants and childrenOral neem oil in infants and young children produces vomiting, drowsiness, tachypnoea and recurrent generalised seizures, with metabolic acidosis and leucocytosis. Liver biopsy findings have shown fatty change in liver and renal tubules with mitochondrial damage, consistent with Reye's syndrome. Case series include thirteen Malaysian children, and a four-month-old infant given margosa oil for cough. Prognosis is usually good, but deaths and neurological deficits are both reported.
Toxic encephalopathy in adultsNeem oil poisoning with toxic encephalopathy is also reported in adults, so this is not solely a question of a child's smaller size.

Growing it

ClimateA hardy evergreen tree of hot, dry and semi-arid regions, long established across South Asia and Africa.
SoilTolerates poor, shallow and stony ground where little else will grow, which is much of why it was planted so widely.
PlantingGrown from seed or nursery-raised saplings. Seed viability is short, so fresh seed matters.
HarvestLeaves are picked as needed; seed is collected when the fruit ripens and falls, and the oil is pressed from the kernel.
What is not statedLaisha holds no sourced per-hectare yield, oil recovery rate or cost figure for neem, and none is offered.

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What this is not

Sources

Margosa Oil — LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
LiverTox, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health · read 2026-09-20
Margosa oil as the neem seed oil of traditional use, the pattern of toxicity in infants and young children, hepatotoxicity and the Reye-like presentation, and the reports of toxic encephalopathy in adults.
https://www.ncbi.nlm.nih.gov/books/NBK548429/
Plant toxins and acute medicinal plant poisoning in children: a systematic literature review
PubMed Central, National Institutes of Health · read 2026-09-20
The clinical picture of neem oil poisoning in children — vomiting, drowsiness, tachypnoea, recurrent seizures, metabolic acidosis and leucocytosis — the Malaysian case series, the four-month-old given margosa oil for cough, the liver and renal mitochondrial findings, and the outcome statement that prognosis is usually good but deaths and neurological deficits occur.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5894275/
Azadirachta indica A.Juss. — GBIF Backbone Taxonomy
Global Biodiversity Information Facility (GBIF), Copenhagen · read 2026-09-20
The accepted botanical name with author, and placement in Meliaceae, matched at 99% confidence.
https://api.gbif.org/v1/species/match?name=Azadirachta%20indica
The Ayurvedic Pharmacopoeia of India — Nimba (Azadirachta indica A.Juss.)
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-28
The official Indian pharmacopoeial standing of the dravya and the identity of the part used as the pharmacopoeial article.
https://pcimh.gov.in/
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it. Sharangadhara is where Ayurveda's dose forms and their measures are set out, and it is what every Dravyaguna textbook reproduces.
https://niimh.nic.in/ebooks/esharangadhara/
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