LAISHA · DRAVYAGUNA

Nirgundi

निर्गुण्डी

Vitex negundo L.

Lamiaceae · Vitex

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

Hindi name: Sambhalu

What the texts say Nirgundi does

What the evidence says. Traditional use is extensive and long recorded. Modern clinical evidence is limited.

Side effects and limits

Avoid or ask first: Pregnancy.

A traditional classification, not a recommendation. The full safety record is below.

Stands in 3 groups

A Samhita can only be read forwards, from the group to its members. This is the same list read backwards.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Patra swarasa10–20 ml
Kwatha50–100 ml
Churna3–6 g
AnupanaUshnodaka · Madhu
KalaAdhobhakta

The classical vatahara and shothahara; largely external as a lepa and in taila.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Rasapanchaka

Rasa
KatuTiktaKashaya
Guna
LaghuRuksha
ViryaUshna
VipakaKatu
PrabhavaThe texts treat nirgundi as vedanasthapana, relieving pain, and as shothahara, and it is the dravya named most often for external application where a joint is swollen.
DoshakarmaKaphavatahara. Being ushna it increases pitta.

Katu, tikta and kashaya with ushna virya and katu vipaka.

Karma and part used

VedanasthapanaShothaharaKrimighnaKushthaghnaKeshyaVatahara

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaPatra (the leaf)
Mula (the root)
Beeja (the seed)
Why it mattersThe leaf is the dravya most used, chiefly externally as a poultice and in oil. The root and seed are used separately.

Paryaya

SinduvaraShephalikaNilikaIndraniSugandhika

Sinduvara is the paryaya the classical texts use. The plant is identified by its leaf, which is palmately compound with five leaflets — hence the English name — and by its aroma when crushed.

Names, by language

EnglishFive-leaved chaste tree
SinhalaNika
NepaliSimali
HindiSambhalu
KannadaLakki
TamilNochi
TeluguVavili
MalayalamKarinochi
MarathiNirgundi
GujaratiNagod
BengaliNishinda
PunjabiBanna
OdiaBegundia
UrduSambhalu

Classical references

Bhavaprakasha Nighantu
Guduchyadi Varga
Gives the rasa, guna, virya and vipaka of nirgundi and distinguishes the white and blue kinds.
Charaka Samhita
Sutrasthana, chapter 4 (Shadvirechanashatashritiya)
Named among the dravya of the chapter.
Sushruta Samhita
Sutrasthana, chapter 38 (Dravyasangrahaniya)
Included among the dravya grouped by action.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check. Where an exact chapter and verse could not be confirmed, this library names the section rather than inventing a number.

Formulations it appears in

Nirgundi TailaAn oil named for the dravya, used externally.
Vishagarbha TailaAmong the principal dravya.
Nirgundi KwathaNamed for the dravya.

Adulterants and substitutes

Vitex trifolia, with three leaflets rather than five, is collected and sold as nirgundi and is a different species. The leaf count is the field test and it is easy to apply while the leaf is whole; once dried and broken it is not.

Identity

Matched live against the GBIF backbone on 28 September 2026 at 99 per cent confidence. The white-flowered and blue-flowered forms are both used and the texts distinguish them as Shweta and Nila Nirgundi.

A WAY TO REMEMBER IT

Vitex is from viere, to weave — the pliant twigs were used for basketry. Negundo is from the Sanskrit nirgundi itself.

What the tradition holds

Nirgundi is described in the Bhavaprakasha Nighantu and is recorded as vedanasthapana and shothahara. That is what the tradition holds and where it is written down, not a finding about what the leaf does in a body.

Constituents. The leaf carries flavonoids including casticin, along with iridoid glycosides and an essential oil.

What the evidence says

StatusTraditional use is extensive and long recorded. Modern clinical evidence is limited.
SuggestedHealth Canada publishes monographs covering Ayurvedic ingredients and permits specific traditional-use claims, which reflects a regulator accepting a documented tradition rather than a body of clinical trial evidence.
Not establishedThere is not enough good clinical evidence to establish an effect on any named health condition. Long traditional use is not a substitute for that evidence, and this library does not present it as one.
The honest gapMost published work concerns extracts applied to skin in animals rather than the leaf as used traditionally.

Safety

Used very widely, chiefly on the outside of the body, and no serious harm is documented at traditional external use. The genus Vitex is documented to affect hormones — the related Vitex agnus-castus is used for exactly that — so this entry treats hormonal interaction as a real caution rather than a theoretical one, and does not recommend it in pregnancy. Anyone on medication, pregnant, or managing a diagnosed condition should speak to a doctor or a qualified practitioner first.

Side effectsSkin irritation on external use in some people
Digestive upset when taken internally
ContraindicationsPregnancy.
InteractionsSedatives — additive sedation reported.
Dopamine agonists and antagonists, and drugs acting on prolactin — Vitex species affect prolactin, so oral contraceptives, dopamine agonists and antipsychotics are the ones to ask about.
Pregnancy and breastfeedingNot to be used in pregnancy. There is not enough evidence to establish safety in breastfeeding.

Growing it

ClimateTropical and subtropical; a hardy shrub found along field margins and watercourses.
SoilAlmost any, including poor ground.
PlantingGrown very easily from cuttings; often planted as a live fence.
HarvestLeaves are picked from established bushes and used fresh for poultice or dried for decoction.
What is not statedThis library has not verified region-specific spacing, variety and yield figures against a named agricultural authority for every growing country, and does not state them rather than guessing.

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What this is not

Sources

GBIF Backbone Taxonomy species-match record for Vitex negundo L.
Global Biodiversity Information Facility (GBIF) · read 2026-09-28
Confirming live, rather than from memory, the accepted botanical name and family behind the Sanskrit name.
https://api.gbif.org/v1/species/match?name=Vitex%20negundo
The Ayurvedic Pharmacopoeia of India — Nirgundi (Vitex negundo L.)
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-28
The official Indian pharmacopoeial standing of the dravya and the identity of the part used as the pharmacopoeial article.
https://pcimh.gov.in/
Compendium of Monographs — Natural Health Products
Health Canada, Natural and Non-prescription Health Products Directorate · read 2026-09-28
A regulator outside India that publishes monographs covering Ayurvedic ingredients — used for the safety framing, and for the line between a permitted traditional-use claim and clinical evidence.
https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/applications-submissions/product-licensing/compendium-monographs.html
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it. Sharangadhara is where Ayurveda's dose forms and their measures are set out, and it is what every Dravyaguna textbook reproduces.
https://niimh.nic.in/ebooks/esharangadhara/
← all dravya