LAISHA · DRAVYAGUNA

Guggulu

गुग्गुलु

Commiphora wightii (Arn.) Bhandari

Burseraceae · Commiphora

Benefits & side effects

TRADITIONAL VIEW, WITH SAFETY LIMITS

What the texts say Guggulu does

What the evidence says. Traditional use is extensive and long recorded. Modern clinical evidence is limited.

Side effects and limits

Avoid or ask first: Pregnancy.; Liver disease.; Bleeding disorders and the period before surgery.

A traditional classification, not a recommendation. The full safety record is below.

Stands in 2 groups

A Samhita can only be read forwards, from the group to its members. This is the same list read backwards.

Photographs

Matra and anupana

AS THE CLASSICAL TEXTS AND THE API PRESCRIBE

Shodhita guggulu1–3 g
AnupanaUshnodaka · Dugdha
KalaAdhobhakta

Used only after shodhana, and always inside a named yoga — Yogaraja, Kaishora, Triphala guggulu — never as raw resin.

Reported from Sharangadhara Samhita and the Ayurvedic Pharmacopoeia of India. Laisha states what the texts prescribe; it does not recommend. No quantity here is adjusted for a particular person — not for agni, koshtha, bala, age, pregnancy, kidney or liver function, or anything already being taken.

Pharmacopoeial standard

Ayurvedic Pharmacopoeia of India, Part I

MarkerGuggulsterones E and Z
AssayAs the monograph gives
Total ashTotal ash not more than 5 per cent
Acid-insoluble ashNot more than 1 per cent
Alcohol-soluble extractiveAlcohol-soluble extractive not less than 27 per cent
Water-soluble extractiveWater-soluble extractive not less than 50 per cent
Foreign matterForeign matter not more than 4 per cent

Guggulu is sold heavily adulterated with other gum resins, sand and bark. A high acid-insoluble ash is the quickest sign of it.

These are the pharmacopoeial limits for the article, not a test Laisha has run on anything. They are here so a practitioner can ask a supplier for a certificate of analysis and know what the numbers on it should say.

Rasapanchaka

Rasa
TiktaKatuKashaya
Guna
LaghuRukshaVishadaSukshma
ViryaUshna
VipakaKatu
PrabhavaThe texts single out guggulu as the chief of lekhana dravya, scraping away accumulation, and as the carrier that takes other dravya into the joints. It is the base of more named formulations than almost any other article.
DoshakarmaTridoshahara, and particularly vatakaphahara.

Tikta, katu and kashaya with ushna virya and katu vipaka.

Karma and part used

LekhanaMedoharaVataharaShothaharaSandhaniyaRasayana

These are the actions the classical texts record. They are statements about what the tradition holds, and this library does not restate them as findings about a human body.

Upayukta angaNiryasa (the oleo-gum-resin)
Why it mattersThe dravya is the gum resin that exudes from an incision in the bark. It is graded by age and colour, and old resin is considered better than new, which is the opposite of most dravya.

Paryaya

DevadhupaKaushikaPuraMahishakshaPalankasha

Devadhupa means the incense of the gods and records its other use. Mahishaksha, buffalo-eyed, is one of the five named grades of the resin, distinguished by colour, and a student is expected to be able to name them.

Names, by language

EnglishIndian bdellium
SinhalaGuggulu
NepaliGuggul
HindiGuggul
KannadaGugil
TamilGukkulu
TeluguGuggipannu
MalayalamGulgulu
MarathiGuggul
GujaratiGugal
BengaliGuggul
PunjabiGuggal
OdiaGuggulu
UrduMuqil

Classical references

Sushruta Samhita
Chikitsasthana, the chapter on medoroga
Guggulu is named among the dravya used where there is excess accumulation in the body.
Bhavaprakasha Nighantu
Karpuradi Varga
Gives the rasa, guna, virya and vipaka of guggulu and names the five grades of the resin.
Charaka Samhita
Sutrasthana, chapter 4 (Shadvirechanashatashritiya)
Named among the dravya of the chapter.

Rasa, guna, virya, vipaka and karma are recorded as the classical texts give them, with the text and section named so a student can open the book and check. Where an exact chapter and verse could not be confirmed, this library names the section rather than inventing a number.

Formulations it appears in

Yogaraja GugguluGuggulu is the base of the formulation.
Kaishora GugguluGuggulu is the base of the formulation.
Triphala GugguluGuggulu with the three fruits.
Gokshuradi GugguluGuggulu with gokshura.

Adulterants and substitutes

Resin of other Commiphora species, chiefly African, is imported and sold as guggulu, and because the article is a lump of resin the substitution is nearly invisible. Sal resin, gum arabic and simple gum are bulked in. Sand and stone have been found in commercial lots, which is the crudest adulteration in this library and the easiest to find if anyone looks. Raw resin must also be purified before use by a specified process, and unpurified resin sold as finished material is a substitution of method rather than of substance.

Identity

Matched live against the GBIF backbone on 28 September 2026 at 99 per cent confidence. Commiphora mukul is a synonym. The dravya is not the plant but what bleeds from it, which makes it one of the few non-plant-part articles in this library. Assessed as critically endangered on the IUCN Red List — the most threatened dravya here.

A WAY TO REMEMBER IT

Commiphora is kommi (gum) + phoros (bearing) — gum-bearing, which is the whole point of the tree. Wightii honours Robert Wight.

What the tradition holds

Guggulu is described in the Bhavaprakasha Nighantu with its five grades and is named in the Sushruta Samhita among dravya used where the body accumulates. That is what the tradition holds and where it is written down, not a finding about what the resin does in a body.

Constituents. The resin carries guggulsterones E and Z, which are the compounds commercial extracts are standardised to, along with a volatile oil and gums.

What the evidence says

StatusTraditional use is extensive and long recorded. Modern clinical evidence is limited.
SuggestedHealth Canada publishes monographs covering Ayurvedic ingredients and permits specific traditional-use claims, which reflects a regulator accepting a documented tradition rather than a body of clinical trial evidence.
Not establishedThere is not enough good clinical evidence to establish an effect on any named health condition. Long traditional use is not a substitute for that evidence, and this library does not present it as one.
The honest gapPublished work uses standardised guggulsterone extracts of a concentration traditional purified resin does not reach.

Safety

Two separate things need saying. First, the plant is critically endangered on the IUCN Red List — decades of tapping, much of it done badly, have destroyed wild stands across Rajasthan and Gujarat, and a tree tapped incorrectly dies. Buying guggulu without knowing its source is a real question and not a fastidious one. Second, on the body: guggulu is documented to reduce the absorption of several prescribed medicines, including propranolol and diltiazem, and it affects thyroid function. Skin rash is the commonest reported adverse effect and can be significant. Anyone on medication, pregnant, or managing a diagnosed condition should speak to a doctor or a qualified practitioner first.

Side effectsSkin rash, which is the commonest reported effect
Digestive upset and loose stool
Headache
ContraindicationsPregnancy.
Liver disease.
Bleeding disorders and the period before surgery.
InteractionsPropranolol and diltiazem — guggulsterones induce CYP3A4 and were shown to REDUCE the bioavailability of both. This is a treatment-failure risk, not a toxicity one.
Thyroid hormone — guggulsterones stimulate thyroid function and can add to levothyroxine.
Warfarin and antiplatelets — antiplatelet activity reported.
Oestrogens and tamoxifen — guggulsterone is a competitive antagonist at several steroid receptors.
Pregnancy and breastfeedingNot to be used in pregnancy or breastfeeding.
Critically endangered in the wildCommiphora wightii is assessed as critically endangered on the IUCN Red List. Wild stands in Rajasthan and Gujarat have been destroyed by over-tapping, and a tree tapped incorrectly does not survive. This is the most threatened species in this library.
It reduces absorption of prescribed medicinesGuggulu is documented to lower blood levels of propranolol and diltiazem. Anyone taking regular medication should tell their doctor before using it, because a medicine that is being absorbed less is a medicine that may stop working.

Growing it

ClimateArid and semi-arid; a thorny shrub of dry rocky country.
SoilPoor, sandy, stony, very well drained. It wants hard ground.
PlantingGrown from cuttings, which strike more reliably than seed. Slow — many years before a plant can be tapped.
HarvestThe resin is taken by incising the bark of an established plant. Correct tapping leaves the plant alive; the over-tapping that destroyed the wild stands did not.
What is not statedCultivation has been established in Gujarat and Rajasthan precisely because the wild plant is nearly gone. Cultivated and correctly tapped resin should be preferred, and this library states that as a matter of record.

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What this is not

Sources

GBIF Backbone Taxonomy species-match record for Commiphora wightii (Arn.) Bhandari
Global Biodiversity Information Facility (GBIF) · read 2026-09-28
Confirming live, rather than from memory, the accepted botanical name and family behind the Sanskrit name.
https://api.gbif.org/v1/species/match?name=Commiphora%20wightii
The Ayurvedic Pharmacopoeia of India — Guggulu (Commiphora wightii)
Pharmacopoeia Commission for Indian Medicine and Homoeopathy, Ministry of Ayush, Government of India · read 2026-09-28
The official Indian pharmacopoeial standing of the dravya and the identity of the part used as the pharmacopoeial article.
https://pcimh.gov.in/
Compendium of Monographs — Natural Health Products
Health Canada, Natural and Non-prescription Health Products Directorate · read 2026-09-28
A regulator outside India that publishes monographs covering Ayurvedic ingredients — used for the safety framing, and for the line between a permitted traditional-use claim and clinical evidence.
https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/applications-submissions/product-licensing/compendium-monographs.html
Classical matra by dose form
Sharangadhara Samhita, Madhyama Khanda
The classical quantity for each dose form, as the standard reference gives it. Sharangadhara is where Ayurveda's dose forms and their measures are set out, and it is what every Dravyaguna textbook reproduces.
https://niimh.nic.in/ebooks/esharangadhara/
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