ICAR AICE-JRF/SRF - Agricultural Statistics, Computer Application, Bioinformatics (PhD admission and fellowship) · India · National Testing Agency for ICAR
Original practice questions written to the published syllabus · not past papersGenetics as a statistical science: segregation and linkage analysis, gene and genotype frequencies, Hardy-Weinberg and the forces that change it, polygenic models, breeding value and dominance, partitioning genetic variance, correlation between relatives and inbreeding. The Veterinary track teaches animal-genetics principles; this goes to the estimation theory.
In the exams: AICE-JRF Ag Stat Unit 3 (heavy: every unit named); ASRB NET Ag Stat (heavy); AICE-JRF Genetics & Plant Breeding (present)
ICAR AICE-JRF/SRF Agricultural Statistics (Unit 3)
Segregation and linkage analysis, Hardy-Weinberg and disequilibrium, selection-mutation-migration equilibria, Fisher's theorem, polygenic models, variance partitioning, correlation between relatives, inbreeding and estimation of genetic parameters.
ICAR AICE-JRF/SRF Genetics & Plant Breeding and Animal Genetics & Breeding
Hardy-Weinberg, linkage, inbreeding, heritability and genetic correlation as used in breeding.
How our questions for ICAR AICE-JRF/SRF spread across the units of Statistical Genetics: Population & Quantitative Genetics. Difficulty: 16 easy, 52 medium, 19 hard.
| Detection and estimation of linkage | 10 | |
| Gene and genotypic frequencies; Hardy-Weinberg equilibrium | 9 | |
| Selection, mutation, migration and their equilibria | 9 | |
| Polygenic systems: breeding value, dominance, average effect and epistasis | 9 | |
| Regular systems of inbreeding and their effects | 9 | |
| Estimation of heritability, repeatability and genetic correlation | 9 | |
| Statistical analysis of segregation ratios | 7 | |
| Disequilibrium due to linkage and sex-linked genes | 7 | |
| Correlation between relatives | 7 | |
| Fisher's fundamental theorem of natural selection | 6 | |
| Partitioning of genetic variance | 5 |
Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.
What map distance does Kosambi's function give for r = 0.15?
C. 15.5 cM
d = (1/4) ln(1.3/0.7) = 0.155 M = 15.5 cM.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
Pooling subpopulations with different allele frequencies gives:
A. An excess of homozygotes
This is the Wahlund effect: pooled subpopulations show fewer heterozygotes than HWE predicts.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
For an X-linked recessive with q = 0.1, what fraction of females is affected?
D. 0.01
Females need two copies: q^2 = 0.01; males are affected at q = 0.1.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
X-linked allele frequencies are 0.6 in females and 0.3 in males. What is the frequency in males next generation?
D. 0.6
Males receive X from mothers: 0.6. Females become (0.6 + 0.3)/2 = 0.45.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
What is the mutation-selection equilibrium for a deleterious recessive?
C. q = sqrt(u/s)
For a dominant deleterious allele p = u/s.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
Robertson's secondary theorem gives the change in a trait mean as:
A. Additive covariance with fitness
It links natural selection to the breeder's equation.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
Why does the average effect depend on allele frequencies?
C. Substitutions change different genotypes
Rare A mainly converts aa to Aa (a + d); common A converts Aa to AA (a - d).
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
How does better experimental design affect heritability on a plot basis?
B. It raises it by reducing error
Smaller environmental variance raises sigma^2 G / sigma^2 P.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
What is the additive relationship between half sibs?
C. 0.25
Twice the coancestry (1/8).
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
Which covariance matrix of breeding values is used in BLUP?
B. A sigma^2 A
A is the numerator relationship matrix.
Further reading: Falconer and Mackay, Introduction to Quantitative Genetics; Hartl and Clark, Principles of Population Genetics
Ten here, 87 in the app. The Laisha app has every practice question we have written to ICAR AICE-JRF/SRF in this subject, marked as you go, with timed papers, a jump-to-unanswered list and a certificate when you pass at 70 per cent.
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