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AVMA ABVS-recognised specialty boards Veterinary Epidemiology & Zoonoses: practice questions

AVMA ABVS-recognised specialty boards · USA · AVMA American Board of Veterinary Specialties; each college runs its own exams

Original practice questions written to the published syllabus · not past papers
6worked here, free
28written to this exam in this subject
10syllabus units

What this subject covers

How disease is measured, studied and controlled in populations, from incidence and prevalence to surveillance and outbreak investigation, plus the major zoonoses and One Health.

In the exams: Nepal NLEV Epidemiology & Public Health 6; SAVC epidemiology 15 and zoonoses 25; EGEL Plus epidemiology 15; ICAR AICE-JRF core group 06

Where the 28 questions fall

How our questions for AVMA ABVS-recognised specialty boards spread across the units of Veterinary Epidemiology & Zoonoses. Difficulty: 0 easy, 10 medium, 18 hard.

Epidemiological study designs5
Evaluation of diagnostic tests: sensitivity and specificity5
Surveillance3
Risk analysis3
Sampling for disease surveys2
Outbreak investigation2
Zoonoses: rabies, brucellosis, tuberculosis and anthrax2
Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis2
One Health2
Transboundary animal diseases and WOAH2

6 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Epidemiological study designs · medium

In a study of mastitis, cows kept on straw yards had more mastitis, but these cows were also older on average, and age independently increases mastitis risk. Age here is best described as a:

  1. Confounder
  2. Effect modifier
  3. Outcome
  4. Source of random error
Answer and working

A. Confounder

A confounder is associated with the exposure, is an independent cause of the outcome and is not on the causal pathway. Age meets all three. It can be controlled by stratification, matching or multivariable analysis. An effect modifier changes the size of the effect across strata, which is a different concept.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

2 · Evaluation of diagnostic tests: sensitivity and specificity · hard

A test with sensitivity 95% and specificity 98% is used to screen a population in which true prevalence is 1%. What is the positive predictive value?

  1. About 95%
  2. About 98%
  3. About 32%
  4. About 3%
Answer and working

C. About 32%

PPV = P x Se/[P x Se + (1 - P)(1 - Sp)] = 0.0095/(0.0095 + 0.0198) = 0.324. At low prevalence false positives outnumber true positives, even with a good test. About 3% is the apparent prevalence (0.0095 + 0.0198 = 0.029), not PPV. 95% is the PPV the same test would reach at about 30% prevalence.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

3 · Evaluation of diagnostic tests: sensitivity and specificity · hard

A serological survey finds apparent prevalence of 12% using a test with sensitivity 90% and specificity 95%. What is the estimated true prevalence (Rogan-Gladen)?

  1. 12%
  2. About 8.2%
  3. About 13.3%
  4. About 7.0%
Answer and working

B. About 8.2%

True prevalence = (AP + Sp - 1)/(Se + Sp - 1) = (0.12 + 0.95 - 1)/(0.90 + 0.95 - 1) = 0.07/0.85 = 0.082. 13.3% is AP/Se, which ignores false positives; 7% forgets the denominator.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

4 · Risk analysis · medium

Under the WTO SPS Agreement, if a country wants an import measure stricter than the relevant WOAH standard, it must:

  1. Obtain approval from FAO
  2. Show that the exporting country has no veterinary service
  3. Apply the same measure to all trading partners regardless of disease status
  4. Justify it with a scientific risk assessment
Answer and working

D. Justify it with a scientific risk assessment

The SPS Agreement allows a higher level of protection than international standards only when it is based on scientific justification or a risk assessment. WOAH is the recognised standard-setting body for animal health.

Further reading: WOAH Terrestrial Animal Health Code

5 · Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis · hard

According to the WOAH Manual criteria, an avian influenza isolate is classified as highly pathogenic if it:

  1. Belongs to any H subtype and causes respiratory signs in infected chickens
  2. Has an intravenous pathogenicity index below 1.2 in six-week-old chickens
  3. Is of subtype N1 regardless of virulence
  4. Has an intravenous pathogenicity index above 1.2 in six-week-old chickens
Answer and working

D. Has an intravenous pathogenicity index above 1.2 in six-week-old chickens

HPAI is defined by an IVPI above 1.2 in six-week-old chickens, or at least 75% mortality in four- to eight-week-old chickens inoculated intravenously, or, for H5 and H7 viruses, a haemagglutinin cleavage site with multiple basic amino acids similar to known HPAI viruses. The N subtype does not define pathogenicity.

Further reading: WOAH Manual of Diagnostic Tests and Vaccines for Terrestrial Animals

6 · Transboundary animal diseases and WOAH · hard

Which event does NOT by itself require an immediate notification to WOAH?

  1. The first occurrence of a listed disease in a zone previously recognised as free
  2. Recurrence of a listed disease after the country had previously declared it eradicated
  3. The first occurrence of a new strain of the agent of a listed disease in the country
  4. A continuing, stable level of a listed disease already reported as present
Answer and working

D. A continuing, stable level of a listed disease already reported as present

Immediate notification covers first occurrences, recurrences after declared eradication, new strains, sudden unexpected changes in distribution, incidence or severity, and emerging diseases of significance. A stable endemic situation is reported in six-monthly reports.

Further reading: WOAH Terrestrial Animal Health Code

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Read the subject

Veterinary Epidemiology & ZoonosesThe full study manual, free AVMA ABVS-recognised specialty boardsFormat, sections and how it has changed

More AVMA ABVS-recognised specialty boards practice

Wildlife, Zoo Animal & Conservation MedicineLaboratory Animal Science & MedicineVeterinary Research Methodology & Evidence-Based Veterinary Medicine

Veterinary Epidemiology & Zoonoses for other exams

ENARE multiprofessional residency · BrazilSAVC Registration Examination · South AfricaICAR AICE-JRF/SRF · IndiaICAR AIEEA · IndiaEGEL Plus MVZ · MexicoNational Licensure Examination for Veterinarians · NepalENADE · BrazilNational Veterinary Examination · JapanAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandNAVLE · USA / CanadaRCVS Statutory Membership Examination · UKEBVS European College diplomas · Europe

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