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National Licensure Examination for Veterinarians Veterinary Epidemiology & Zoonoses: practice questions

National Licensure Examination for Veterinarians (NLEV) · Nepal · Nepal Veterinary Council (NVC Act 2055 BS)

Original practice questions written to the published syllabus · not past papers
10worked here, free
50written to this exam in this subject
12syllabus units

What this subject covers

How disease is measured, studied and controlled in populations, from incidence and prevalence to surveillance and outbreak investigation, plus the major zoonoses and One Health.

In the exams: Nepal NLEV Epidemiology & Public Health 6; SAVC epidemiology 15 and zoonoses 25; EGEL Plus epidemiology 15; ICAR AICE-JRF core group 06

Where the 50 questions fall

How our questions for National Licensure Examination for Veterinarians spread across the units of Veterinary Epidemiology & Zoonoses. Difficulty: 21 easy, 26 medium, 3 hard.

Zoonoses: rabies, brucellosis, tuberculosis and anthrax7
Measures of disease frequency: incidence, prevalence, morbidity, mortality and case fatality6
Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis6
Evaluation of diagnostic tests: sensitivity and specificity5
Epidemiological study designs4
Sampling for disease surveys4
Outbreak investigation4
Terms of disease occurrence: sporadic, enzootic, epizootic, panzootic and exotic3
Surveillance3
Risk analysis3
Transboundary animal diseases and WOAH3
One Health2

10 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Terms of disease occurrence: sporadic, enzootic, epizootic, panzootic and exotic · easy

A disease that is present in a cattle population at a usual, fairly constant and predictable frequency is described as:

  1. Enzootic
  2. Epizootic
  3. Sporadic
  4. Exotic
Answer and working

A. Enzootic

Enzootic (the animal equivalent of endemic) means present at the expected, stable level. Epizootic means clearly above the expected level; sporadic means irregular and unpredictable; exotic means not normally present in the country.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

2 · Measures of disease frequency: incidence, prevalence, morbidity, mortality and case fatality · easy

During an outbreak of respiratory disease, 40 calves become ill and 6 of them die. What is the case fatality rate?

  1. 6%
  2. 17.6%
  3. 40%
  4. 15%
Answer and working

D. 15%

Case fatality = deaths / cases = 6/40 = 15%. It measures severity. Dividing deaths by the whole herd gives mortality, not case fatality; 17.6% divides by the 34 survivors (6/34).

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

3 · Epidemiological study designs · medium

A case-control study of salmonellosis in herds gives: cases exposed 40, cases unexposed 60, controls exposed 20, controls unexposed 80. What is the odds ratio?

  1. 2.67
  2. 1.56
  3. 2.00
  4. 0.38
Answer and working

A. 2.67

OR = ad/bc = (40 x 80)/(20 x 60) = 3200/1200 = 2.67. 2.00 is 40/20, a ratio of exposed counts. 1.56 comes from treating the table as if risks could be computed, which a case-control design does not allow. 0.38 is the inverse.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

4 · Surveillance · easy

A national system relies on farmers and private veterinarians to report suspect cases of disease to the veterinary authority. This is:

  1. Passive surveillance
  2. Targeted active surveillance
  3. Sentinel surveillance
  4. Participatory surveillance
Answer and working

A. Passive surveillance

Passive surveillance depends on reports initiated by others. It is continuous and cheap but misses mild or unrecognised disease. Active surveillance is initiated by the authority through planned sampling.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

5 · Outbreak investigation · medium

In a feed-associated outbreak, 80 broilers received a particular batch of feed and 20 became ill. What is the attack rate among birds that received it?

  1. 20%
  2. 4%
  3. 25%
  4. 80%
Answer and working

C. 25%

Attack rate = ill / exposed = 20/80 = 25%. The value is compared with the attack rate in birds not fed that batch to implicate or exonerate it. 4% inverts the ratio (80/20 = 4).

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

6 · Zoonoses: rabies, brucellosis, tuberculosis and anthrax · easy

A cow is found dead with dark unclotted blood oozing from the nostrils and anus and no rigor mortis. What should be done first?

  1. Perform a full necropsy at once to examine the spleen for enlargement and to collect tissue samples from every organ
  2. Skin the carcass carefully to salvage the hide, then bury the remains at least two metres deep on the same farm
  3. Do not open the carcass; take a peripheral blood smear for polychrome methylene blue stain and inform the authorities
  4. Send the carcass for rendering without delay so that no other animals can feed on it
Answer and working

C. Do not open the carcass; take a peripheral blood smear for polychrome methylene blue stain and inform the authorities

These signs suggest anthrax. Opening the carcass exposes vegetative bacilli to air, and they then sporulate and contaminate the site for decades. A blood smear shows square-ended bacilli with a pink capsule (M'Fadyean reaction). The case must be reported and the carcass destroyed as national rules require.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

7 · Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis · medium

Which serovar-maintenance host pairing for Leptospira is correct?

  1. Canicola in rats
  2. Hardjo in cattle
  3. Icterohaemorrhagiae in cattle
  4. Pomona in dogs
Answer and working

B. Hardjo in cattle

Typical pairings are Icterohaemorrhagiae in rats, Hardjo in cattle, Pomona and Bratislava in pigs and Canicola in dogs. The distractors swap the hosts.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

8 · Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis · medium

Why are H5 and H7 low pathogenicity avian influenza viruses in poultry a regulatory concern?

  1. They are always highly pathogenic for humans and spread readily from person to person after any exposure to poultry
  2. HPAI viruses have so far arisen only from H5 and H7 subtypes, which can mutate to high pathogenicity in poultry
  3. They cannot be detected by any laboratory test, so infected flocks go unnoticed until they die
  4. They infect only mammals
Answer and working

B. HPAI viruses have so far arisen only from H5 and H7 subtypes, which can mutate to high pathogenicity in poultry

HPAI has emerged from H5 and H7 LPAI precursors through changes at the haemagglutinin cleavage site during circulation in poultry, so these subtypes are monitored even when mild.

Further reading: WOAH Manual of Diagnostic Tests and Vaccines for Terrestrial Animals

9 · Measures of disease frequency: incidence, prevalence, morbidity, mortality and case fatality · easy

Point prevalence measured in a single cross-sectional survey is most useful for:

  1. Estimating the risk that a healthy animal will become diseased during the next month
  2. Estimating the current burden of disease to plan treatment or control work
  3. Measuring the speed at which new cases occur
  4. Measuring how often diseased animals die
Answer and working

B. Estimating the current burden of disease to plan treatment or control work

Prevalence describes how much disease exists at one time, useful for planning. Risk and speed of new cases are incidence measures; how often cases die is case fatality.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

10 · Surveillance · easy

Planned testing of a random sample of herds by the veterinary authority to measure brucellosis prevalence is an example of:

  1. Passive surveillance
  2. Syndromic surveillance
  3. Active surveillance
  4. Participatory surveillance
Answer and working

C. Active surveillance

The authority initiates and designs the data collection, so it is active surveillance.

Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.

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Read the subject

Veterinary Epidemiology & ZoonosesThe full study manual, free National Licensure Examination for VeterinariansFormat, sections and how it has changed

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Veterinary Epidemiology & Zoonoses for other exams

ENARE multiprofessional residency · BrazilSAVC Registration Examination · South AfricaICAR AICE-JRF/SRF · IndiaICAR AIEEA · IndiaEGEL Plus MVZ · MexicoENADE · BrazilNational Veterinary Examination · JapanAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandNAVLE · USA / CanadaRCVS Statutory Membership Examination · UKAVMA ABVS-recognised specialty boards · USAEBVS European College diplomas · Europe

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