RCVS Statutory Membership Examination (SME) · UK · Royal College of Veterinary Surgeons
Original practice questions written to the published syllabus · not past papersHow disease is measured, studied and controlled in populations, from incidence and prevalence to surveillance and outbreak investigation, plus the major zoonoses and One Health.
In the exams: Nepal NLEV Epidemiology & Public Health 6; SAVC epidemiology 15 and zoonoses 25; EGEL Plus epidemiology 15; ICAR AICE-JRF core group 06
How our questions for RCVS Statutory Membership Examination spread across the units of Veterinary Epidemiology & Zoonoses. Difficulty: 12 easy, 14 medium, 4 hard.
| Evaluation of diagnostic tests: sensitivity and specificity | 5 | |
| Zoonoses: rabies, brucellosis, tuberculosis and anthrax | 4 | |
| Outbreak investigation | 3 | |
| Zoonoses: leptospirosis, glanders, KFD, avian influenza and Japanese encephalitis | 3 | |
| Terms of disease occurrence: sporadic, enzootic, epizootic, panzootic and exotic | 2 | |
| Measures of disease frequency: incidence, prevalence, morbidity, mortality and case fatality | 2 | |
| Epidemiological study designs | 2 | |
| Sampling for disease surveys | 2 | |
| Surveillance | 2 | |
| Risk analysis | 2 | |
| One Health | 2 | |
| Transboundary animal diseases and WOAH | 1 |
Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.
During an outbreak of respiratory disease, 40 calves become ill and 6 of them die. What is the case fatality rate?
D. 15%
Case fatality = deaths / cases = 6/40 = 15%. It measures severity. Dividing deaths by the whole herd gives mortality, not case fatality; 17.6% divides by the 34 survivors (6/34).
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
A national system relies on farmers and private veterinarians to report suspect cases of disease to the veterinary authority. This is:
A. Passive surveillance
Passive surveillance depends on reports initiated by others. It is continuous and cheap but misses mild or unrecognised disease. Active surveillance is initiated by the authority through planned sampling.
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
A test applied to 1,000 animals gives TP 90, FN 10, FP 45 and TN 855. What is the negative predictive value?
A. 98.8%
NPV = TN/(TN + FN) = 855/865 = 0.988. 95% is the specificity, which students often give instead; 66.7% is the PPV (90/135).
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
In a feed-associated outbreak, 80 broilers received a particular batch of feed and 20 became ill. What is the attack rate among birds that received it?
C. 25%
Attack rate = ill / exposed = 20/80 = 25%. The value is compared with the attack rate in birds not fed that batch to implicate or exonerate it. 4% inverts the ratio (80/20 = 4).
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
A healthy, vaccinated pet dog bites a person. Under the approach used in many countries, what is the standard animal-side step?
B. Observe the dog for 10 days; if it stays healthy it was not shedding rabies virus when it bit
Dogs, cats and ferrets shed virus in saliva only shortly before signs appear, so a 10-day observation period is widely used. National rules decide details and whether human prophylaxis starts at once. A blood antibody titre does not show whether the dog is infected.
Further reading: WOAH Terrestrial Animal Health Code
In a brucellosis programme, the Rose Bengal test is followed by the complement fixation test only in Rose Bengal-positive animals. What is the effect of this series interpretation?
D. Specificity increases and sensitivity decreases compared with either test alone
Series testing (positive only if both are positive) raises specificity and lowers sensitivity. It is used to confirm reactors before slaughter. Because both are antibody tests, they are not fully independent and the gain is smaller than the formula predicts.
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
After severe floods, several rice farmers are admitted with fever, jaundice and kidney failure. Which zoonosis is the most likely cause?
D. Leptospirosis
Leptospires shed in rodent and livestock urine survive in flood water and wet soil. Fever with jaundice and renal failure is Weil's disease. Floods are a classic trigger for human leptospirosis clusters.
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
Why are H5 and H7 low pathogenicity avian influenza viruses in poultry a regulatory concern?
B. HPAI viruses have so far arisen only from H5 and H7 subtypes, which can mutate to high pathogenicity in poultry
HPAI has emerged from H5 and H7 LPAI precursors through changes at the haemagglutinin cleavage site during circulation in poultry, so these subtypes are monitored even when mild.
Further reading: WOAH Manual of Diagnostic Tests and Vaccines for Terrestrial Animals
Point prevalence measured in a single cross-sectional survey is most useful for:
B. Estimating the current burden of disease to plan treatment or control work
Prevalence describes how much disease exists at one time, useful for planning. Risk and speed of new cases are incidence measures; how often cases die is case fatality.
Further reading: Thrusfield M et al., Veterinary Epidemiology, 4th ed.
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