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Kenya Veterinary Board pre-registration exam Veterinary Pharmacy, Prescribing Law & Medicines Regulation: practice questions

Kenya Veterinary Board pre-registration exam · Kenya · Kenya Veterinary Board (VSVP Act 2011)

Original practice questions written to the published syllabus · not past papers
7worked here, free
26written to this exam in this subject
5syllabus units

What this subject covers

Writing a lawful prescription and dispensing safely: who may prescribe, extra-label use and the cascade, withdrawal periods and MRLs, drugs prohibited in food animals, pharmacovigilance, controlled drugs and records.

In the exams: EAEVE Day One competences on prescribing, dispensing and reporting adverse reactions; WOAH Day 1 veterinary products; RCVS Day One competences (the cascade)

Where the 26 questions fall

How our questions for Kenya Veterinary Board pre-registration exam spread across the units of Veterinary Pharmacy, Prescribing Law & Medicines Regulation. Difficulty: 14 easy, 12 medium, 0 hard.

Dispensing12
Prescription writing5
Pharmacovigilance and adverse-event reporting5
Withdrawal periods2
Record keeping2

7 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Dispensing · easy

An owner asks whether she can crush an enteric-coated tablet to hide it in food for her dog. What is the correct advice?

  1. Yes, provided the powder is mixed into a fatty food
  2. No, but it may be split into quarters without any loss of effect
  3. Yes; all tablets work the same once they have been crushed
  4. No; crushing defeats the protective enteric coating
Answer and working

D. No; crushing defeats the protective enteric coating

An enteric coating stops the tablet dissolving in the stomach, either to protect the drug from acid or to protect the stomach from the drug. Crushing or splitting defeats it. Ask for a different formulation instead.

2 · Dispensing · medium

A multi-dose injectable vial was first broached 35 days ago. Its SPC gives an in-use shelf life of 28 days. Half the liquid remains and the printed expiry date is next year. What should be done?

  1. Refrigerate it to reset the in-use shelf life for another 28 days
  2. Use it, because the printed expiry date has not yet been reached
  3. Use it for non-urgent cases only, until the printed expiry date
  4. Discard it; the in-use shelf life has ended
Answer and working

D. Discard it; the in-use shelf life has ended

Once a vial is broached, the in-use shelf life in the SPC applies, because of the risk of contamination and degradation. The printed expiry applies only to unopened product. Mark the opening date on every vial.

3 · Dispensing · easy

How many milligrams of drug are there in 1 mL of a 2% w/v solution?

  1. 2 mg
  2. 0.2 mg
  3. 200 mg
  4. 20 mg
Answer and working

D. 20 mg

2% w/v = 2 g per 100 mL = 2000 mg per 100 mL = 20 mg/mL. Rule of thumb: % w/v × 10 = mg/mL. 2 mg and 200 mg are tenfold slips in either direction; 0.2 mg divides by 10 instead of multiplying.

4 · Dispensing · easy

Adrenaline (epinephrine) is supplied as a 1:1000 solution. What is its concentration?

  1. 0.1 mg/mL
  2. 1 mg/mL
  3. 10 mg/mL
  4. 0.01 mg/mL
Answer and working

B. 1 mg/mL

Ratio strength 1:1000 for a solid in a liquid means 1 g in 1000 mL, which is 1 mg/mL. 0.1 mg/mL is the 1:10,000 strength; confusing the two is a classic tenfold error.

5 · Dispensing · easy

5 g of a drug is dissolved and made up to 250 mL. What is the strength as % w/v?

  1. 0.2%
  2. 2%
  3. 20%
  4. 5%
Answer and working

B. 2%

% w/v = g per 100 mL. 5 g in 250 mL = 2 g in 100 mL = 2%. 20% and 0.2% are tenfold slips; 5% ignores the volume.

6 · Withdrawal periods · medium

A vet gives a calf double the labelled dose of an antibiotic. Why is the label withdrawal period no longer reliable?

  1. Withdrawal depends only on the route of administration, never on the dose
  2. A higher dose speeds up elimination, so the label withdrawal becomes too long
  3. More drug must be cleared, so residues could exceed the MRL at label time
  4. Labels always build in a margin for a doubled dose, so nothing changes at all
Answer and working

C. More drug must be cleared, so residues could exceed the MRL at label time

Withdrawal periods come from depletion studies at the labelled dose, route and duration. More drug, a longer course or a different route can leave residues above the MRL after the label time.

7 · Pharmacovigilance and adverse-event reporting · easy

A farmer reports that a wormer, given correctly, no longer reduces faecal egg counts in his sheep. Is this a reportable adverse event?

  1. No; poor efficacy is a commercial matter for the seller
  2. Only if a sheep dies after treatment with the wormer
  3. Yes; lack of expected efficacy is reportable
  4. No; only reactions in the treated animals are reported
Answer and working

C. Yes; lack of expected efficacy is reportable

Veterinary pharmacovigilance includes lack of expected efficacy, which may signal resistance. Reports help regulators and companies spot emerging anthelmintic or antimicrobial resistance.

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Read the subject

Veterinary Pharmacy, Prescribing Law & Medicines RegulationThe full study manual, free Kenya Veterinary Board pre-registration examFormat, sections and how it has changed

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Veterinary Pharmacy, Prescribing Law & Medicines Regulation for other exams

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