SAVC Registration Examination · South Africa · South African Veterinary Council
Original practice questions written to the published syllabus · not past papersWriting a lawful prescription and dispensing safely: who may prescribe, extra-label use and the cascade, withdrawal periods and MRLs, drugs prohibited in food animals, pharmacovigilance, controlled drugs and records.
In the exams: EAEVE Day One competences on prescribing, dispensing and reporting adverse reactions; WOAH Day 1 veterinary products; RCVS Day One competences (the cascade)
Australasian Veterinary Examination and SAVC Registration Examination
Prescribing and off-label use with withholding periods in food animals, residue control, controlled drugs and records, and dose calculation; SAVC Paper 4 also covers national medicines law in outline.
How our questions for SAVC Registration Examination spread across the units of Veterinary Pharmacy, Prescribing Law & Medicines Regulation. Difficulty: 14 easy, 21 medium, 3 hard.
| Dispensing | 17 | |
| Prescription writing | 6 | |
| Pharmacovigilance and adverse-event reporting | 5 | |
| Withdrawal periods | 4 | |
| Maximum residue limits | 2 | |
| Record keeping | 2 | |
| Extra-label use: US AMDUCA and the UK cascade | 1 | |
| Drugs prohibited in food-producing animals | 1 |
Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.
A 15 kg dog is prescribed a drug at 2 mg/kg by mouth once daily for 14 days, using 10 mg tablets. How many tablets should be dispensed?
A. 42 tablets
Dose = 2 × 15 = 30 mg = 3 tablets daily; 3 × 14 = 42 tablets. 21 halves the course; 84 treats once daily as twice daily; 30 confuses the 30 mg dose with a tablet count. Illustrative drug only. Confirm any real dose against the product label and your national formulary.
An owner asks whether she can crush an enteric-coated tablet to hide it in food for her dog. What is the correct advice?
D. No; crushing defeats the protective enteric coating
An enteric coating stops the tablet dissolving in the stomach, either to protect the drug from acid or to protect the stomach from the drug. Crushing or splitting defeats it. Ask for a different formulation instead.
A multi-dose injectable vial was first broached 35 days ago. Its SPC gives an in-use shelf life of 28 days. Half the liquid remains and the printed expiry date is next year. What should be done?
D. Discard it; the in-use shelf life has ended
Once a vial is broached, the in-use shelf life in the SPC applies, because of the risk of contamination and degradation. The printed expiry applies only to unopened product. Mark the opening date on every vial.
A horse is euthanased with an overdose of pentobarbital on a farm. Why must the carcass be disposed of securely and not left for scavengers?
B. Pentobarbital residues in the carcass can kill dogs and wild scavengers that eat it
Pentobarbital persists in the tissues of euthanased animals and has killed dogs, eagles and other scavengers (relay toxicosis). Secure burial or rendering, as local rules allow, prevents this.
How many milligrams of drug are there in 1 mL of a 2% w/v solution?
D. 20 mg
2% w/v = 2 g per 100 mL = 2000 mg per 100 mL = 20 mg/mL. Rule of thumb: % w/v × 10 = mg/mL. 2 mg and 200 mg are tenfold slips in either direction; 0.2 mg divides by 10 instead of multiplying.
Adrenaline (epinephrine) is supplied as a 1:1000 solution. What is its concentration?
B. 1 mg/mL
Ratio strength 1:1000 for a solid in a liquid means 1 g in 1000 mL, which is 1 mg/mL. 0.1 mg/mL is the 1:10,000 strength; confusing the two is a classic tenfold error.
5 g of a drug is dissolved and made up to 250 mL. What is the strength as % w/v?
B. 2%
% w/v = g per 100 mL. 5 g in 250 mL = 2 g in 100 mL = 2%. 20% and 0.2% are tenfold slips; 5% ignores the volume.
A vet gives a calf double the labelled dose of an antibiotic. Why is the label withdrawal period no longer reliable?
C. More drug must be cleared, so residues could exceed the MRL at label time
Withdrawal periods come from depletion studies at the labelled dose, route and duration. More drug, a longer course or a different route can leave residues above the MRL after the label time.
A cow treated with a dry-cow intramammary product calves earlier than expected, before the product's minimum dry period has passed. When can her milk enter the food chain?
B. Only when both the minimum dry period and the milk withdrawal are met
Dry-cow products are long-acting and their withdrawal assumes a minimum dry period. If calving comes early, milk is withheld until both conditions are met, and a residue test helps confirm.
A farmer reports that a wormer, given correctly, no longer reduces faecal egg counts in his sheep. Is this a reportable adverse event?
C. Yes; lack of expected efficacy is reportable
Veterinary pharmacovigilance includes lack of expected efficacy, which may signal resistance. Reports help regulators and companies spot emerging anthelmintic or antimicrobial resistance.
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