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SAVC Registration Examination Veterinary Pharmacy, Prescribing Law & Medicines Regulation: practice questions

SAVC Registration Examination · South Africa · South African Veterinary Council

Original practice questions written to the published syllabus · not past papers
10worked here, free
38written to this exam in this subject
8syllabus units

What this subject covers

Writing a lawful prescription and dispensing safely: who may prescribe, extra-label use and the cascade, withdrawal periods and MRLs, drugs prohibited in food animals, pharmacovigilance, controlled drugs and records.

In the exams: EAEVE Day One competences on prescribing, dispensing and reporting adverse reactions; WOAH Day 1 veterinary products; RCVS Day One competences (the cascade)

What SAVC Registration Examination asks from it

Australasian Veterinary Examination and SAVC Registration Examination

Prescribing and off-label use with withholding periods in food animals, residue control, controlled drugs and records, and dose calculation; SAVC Paper 4 also covers national medicines law in outline.

Where the 38 questions fall

How our questions for SAVC Registration Examination spread across the units of Veterinary Pharmacy, Prescribing Law & Medicines Regulation. Difficulty: 14 easy, 21 medium, 3 hard.

Dispensing17
Prescription writing6
Pharmacovigilance and adverse-event reporting5
Withdrawal periods4
Maximum residue limits2
Record keeping2
Extra-label use: US AMDUCA and the UK cascade1
Drugs prohibited in food-producing animals1

10 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Prescription writing · medium

A 15 kg dog is prescribed a drug at 2 mg/kg by mouth once daily for 14 days, using 10 mg tablets. How many tablets should be dispensed?

  1. 42 tablets
  2. 30 tablets
  3. 21 tablets
  4. 84 tablets
Answer and working

A. 42 tablets

Dose = 2 × 15 = 30 mg = 3 tablets daily; 3 × 14 = 42 tablets. 21 halves the course; 84 treats once daily as twice daily; 30 confuses the 30 mg dose with a tablet count. Illustrative drug only. Confirm any real dose against the product label and your national formulary.

2 · Dispensing · easy

An owner asks whether she can crush an enteric-coated tablet to hide it in food for her dog. What is the correct advice?

  1. Yes, provided the powder is mixed into a fatty food
  2. No, but it may be split into quarters without any loss of effect
  3. Yes; all tablets work the same once they have been crushed
  4. No; crushing defeats the protective enteric coating
Answer and working

D. No; crushing defeats the protective enteric coating

An enteric coating stops the tablet dissolving in the stomach, either to protect the drug from acid or to protect the stomach from the drug. Crushing or splitting defeats it. Ask for a different formulation instead.

3 · Dispensing · medium

A multi-dose injectable vial was first broached 35 days ago. Its SPC gives an in-use shelf life of 28 days. Half the liquid remains and the printed expiry date is next year. What should be done?

  1. Refrigerate it to reset the in-use shelf life for another 28 days
  2. Use it, because the printed expiry date has not yet been reached
  3. Use it for non-urgent cases only, until the printed expiry date
  4. Discard it; the in-use shelf life has ended
Answer and working

D. Discard it; the in-use shelf life has ended

Once a vial is broached, the in-use shelf life in the SPC applies, because of the risk of contamination and degradation. The printed expiry applies only to unopened product. Mark the opening date on every vial.

4 · Dispensing · medium

A horse is euthanased with an overdose of pentobarbital on a farm. Why must the carcass be disposed of securely and not left for scavengers?

  1. Leaving it exposed lets pentobarbital leach out and reach a safe level
  2. Pentobarbital residues in the carcass can kill dogs and wild scavengers that eat it
  3. Pentobarbital residues make the meat safe to eat but illegal to sell
  4. The drug breaks down into a gas that harms people near the carcass
Answer and working

B. Pentobarbital residues in the carcass can kill dogs and wild scavengers that eat it

Pentobarbital persists in the tissues of euthanased animals and has killed dogs, eagles and other scavengers (relay toxicosis). Secure burial or rendering, as local rules allow, prevents this.

5 · Dispensing · easy

How many milligrams of drug are there in 1 mL of a 2% w/v solution?

  1. 2 mg
  2. 0.2 mg
  3. 200 mg
  4. 20 mg
Answer and working

D. 20 mg

2% w/v = 2 g per 100 mL = 2000 mg per 100 mL = 20 mg/mL. Rule of thumb: % w/v × 10 = mg/mL. 2 mg and 200 mg are tenfold slips in either direction; 0.2 mg divides by 10 instead of multiplying.

6 · Dispensing · easy

Adrenaline (epinephrine) is supplied as a 1:1000 solution. What is its concentration?

  1. 0.1 mg/mL
  2. 1 mg/mL
  3. 10 mg/mL
  4. 0.01 mg/mL
Answer and working

B. 1 mg/mL

Ratio strength 1:1000 for a solid in a liquid means 1 g in 1000 mL, which is 1 mg/mL. 0.1 mg/mL is the 1:10,000 strength; confusing the two is a classic tenfold error.

7 · Dispensing · easy

5 g of a drug is dissolved and made up to 250 mL. What is the strength as % w/v?

  1. 0.2%
  2. 2%
  3. 20%
  4. 5%
Answer and working

B. 2%

% w/v = g per 100 mL. 5 g in 250 mL = 2 g in 100 mL = 2%. 20% and 0.2% are tenfold slips; 5% ignores the volume.

8 · Withdrawal periods · medium

A vet gives a calf double the labelled dose of an antibiotic. Why is the label withdrawal period no longer reliable?

  1. Withdrawal depends only on the route of administration, never on the dose
  2. A higher dose speeds up elimination, so the label withdrawal becomes too long
  3. More drug must be cleared, so residues could exceed the MRL at label time
  4. Labels always build in a margin for a doubled dose, so nothing changes at all
Answer and working

C. More drug must be cleared, so residues could exceed the MRL at label time

Withdrawal periods come from depletion studies at the labelled dose, route and duration. More drug, a longer course or a different route can leave residues above the MRL after the label time.

9 · Withdrawal periods · medium

A cow treated with a dry-cow intramammary product calves earlier than expected, before the product's minimum dry period has passed. When can her milk enter the food chain?

  1. Immediately after calving, because colostrum clears all residues
  2. Only when both the minimum dry period and the milk withdrawal are met
  3. After the post-calving milk withdrawal only, whatever the calving date
  4. After 24 hours, because dry-cow products are designed to leave the udder quickly
Answer and working

B. Only when both the minimum dry period and the milk withdrawal are met

Dry-cow products are long-acting and their withdrawal assumes a minimum dry period. If calving comes early, milk is withheld until both conditions are met, and a residue test helps confirm.

10 · Pharmacovigilance and adverse-event reporting · easy

A farmer reports that a wormer, given correctly, no longer reduces faecal egg counts in his sheep. Is this a reportable adverse event?

  1. No; poor efficacy is a commercial matter for the seller
  2. Only if a sheep dies after treatment with the wormer
  3. Yes; lack of expected efficacy is reportable
  4. No; only reactions in the treated animals are reported
Answer and working

C. Yes; lack of expected efficacy is reportable

Veterinary pharmacovigilance includes lack of expected efficacy, which may signal resistance. Reports help regulators and companies spot emerging anthelmintic or antimicrobial resistance.

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Read the subject

Veterinary Pharmacy, Prescribing Law & Medicines RegulationThe full study manual, free SAVC Registration ExaminationFormat, sections and how it has changed

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Veterinary Pharmacy, Prescribing Law & Medicines Regulation for other exams

RCVS Statutory Membership Examination · UKNAVLE · USA / CanadaAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandVeterinary Council of Ireland registration exam · IrelandNational Licensure Examination for Veterinarians · NepalKenya Veterinary Board pre-registration exam · Kenya

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