Australasian Veterinary Examination (AVE), formerly the National Veterinary Examination (NVE) · Australia / New Zealand · Australasian Veterinary Boards Council (AVBC)
Original practice questions written to the published syllabus · not past papersWriting a lawful prescription and dispensing safely: who may prescribe, extra-label use and the cascade, withdrawal periods and MRLs, drugs prohibited in food animals, pharmacovigilance, controlled drugs and records.
In the exams: EAEVE Day One competences on prescribing, dispensing and reporting adverse reactions; WOAH Day 1 veterinary products; RCVS Day One competences (the cascade)
How our questions for Australasian Veterinary Examination, formerly the National Veterinary Examination spread across the units of Veterinary Pharmacy, Prescribing Law & Medicines Regulation. Difficulty: 17 easy, 23 medium, 6 hard.
| Dispensing | 20 | |
| Prescription writing | 8 | |
| Withdrawal periods | 7 | |
| Pharmacovigilance and adverse-event reporting | 6 | |
| Record keeping | 3 | |
| Extra-label use: US AMDUCA and the UK cascade | 1 | |
| Maximum residue limits | 1 |
Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.
A label reads 'Apply 1 drop OD'. The owner of a dog with an ulcer in the right eye puts one drop in the left eye once a day, reading OD as 'once daily'. What is the best prescribing practice to prevent this?
D. Write the eye and the frequency in plain words, such as right eye once a day
OD means right eye (oculus dexter) to one reader and once daily to another. Plain words on the label remove the ambiguity. Treating both eyes (OU) exposes a healthy eye to a drug it does not need, and verbal explanation is forgotten.
An owner asks whether she can crush an enteric-coated tablet to hide it in food for her dog. What is the correct advice?
D. No; crushing defeats the protective enteric coating
An enteric coating stops the tablet dissolving in the stomach, either to protect the drug from acid or to protect the stomach from the drug. Crushing or splitting defeats it. Ask for a different formulation instead.
A multi-dose injectable vial was first broached 35 days ago. Its SPC gives an in-use shelf life of 28 days. Half the liquid remains and the printed expiry date is next year. What should be done?
D. Discard it; the in-use shelf life has ended
Once a vial is broached, the in-use shelf life in the SPC applies, because of the risk of contamination and degradation. The printed expiry applies only to unopened product. Mark the opening date on every vial.
A horse is euthanased with an overdose of pentobarbital on a farm. Why must the carcass be disposed of securely and not left for scavengers?
B. Pentobarbital residues in the carcass can kill dogs and wild scavengers that eat it
Pentobarbital persists in the tissues of euthanased animals and has killed dogs, eagles and other scavengers (relay toxicosis). Secure burial or rendering, as local rules allow, prevents this.
5 g of a drug is dissolved and made up to 250 mL. What is the strength as % w/v?
B. 2%
% w/v = g per 100 mL. 5 g in 250 mL = 2 g in 100 mL = 2%. 20% and 0.2% are tenfold slips; 5% ignores the volume.
A vet gives a calf double the labelled dose of an antibiotic. Why is the label withdrawal period no longer reliable?
C. More drug must be cleared, so residues could exceed the MRL at label time
Withdrawal periods come from depletion studies at the labelled dose, route and duration. More drug, a longer course or a different route can leave residues above the MRL after the label time.
Under Article 115 of Regulation (EU) 2019/6, a product authorised for cattle with a zero meat withdrawal is used under the cascade in turkeys. What is the minimum meat withdrawal?
A. 1 day
When a product with a zero withdrawal period is used in a different taxonomic family, the EU minimum is 1 day for meat. Zero is the label figure for the authorised species only; 28 days is for products not authorised in food animals.
Further reading: Regulation (EU) 2019/6, Article 115
A farmer reports that a wormer, given correctly, no longer reduces faecal egg counts in his sheep. Is this a reportable adverse event?
C. Yes; lack of expected efficacy is reportable
Veterinary pharmacovigilance includes lack of expected efficacy, which may signal resistance. Reports help regulators and companies spot emerging anthelmintic or antimicrobial resistance.
Milk from a cow tests positive for residues above the MRL even though the farmer observed the label withdrawal period exactly. How should this be treated?
B. As an adverse event suggesting the label withdrawal is too short
A residue violation after the correct withdrawal is part of the scope of pharmacovigilance in the EU and GB. Reports can lead to a review of the withdrawal period.
Under EU rules, keepers of food-producing animals must keep records of medicines bought and given. For how long at minimum?
D. 5 years
Regulation 2019/6 requires keepers of food-producing animals to keep medicine records for at least five years, so residue investigations can trace treatments after the animal has gone.
Further reading: Regulation (EU) 2019/6, Article 108
Ten here, 46 in the app. The Laisha app has every practice question we have written to Australasian Veterinary Examination, formerly the National Veterinary Examination in this subject, marked as you go, with timed papers, a jump-to-unanswered list and a certificate when you pass at 70 per cent.
Free for ten days, then one subscription of US$10 a month. We would rather say so here than have you find it later.
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