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National Veterinary Examination Systematic Veterinary Virology: practice questions

National Veterinary Examination (獣医師国家試験) · Japan · Ministry of Agriculture, Forestry and Fisheries (MAFF), with the Veterinary Affairs Council

Original practice questions written to the published syllabus · not past papers
6worked here, free
24written to this exam in this subject
14syllabus units

What this subject covers

Virus structure and replication, the virus families behind the major animal plagues and pet diseases, and how viral infections are diagnosed and vaccinated against.

In the exams: ICAR AICE-JRF core group 06; ICAR AIEEA-PG 13 (Microbiology); China infectious diseases 30

Where the 24 questions fall

How our questions for National Veterinary Examination spread across the units of Systematic Veterinary Virology. Difficulty: 4 easy, 20 medium, 0 hard.

Canine parvovirus and canine distemper virus5
Equine influenza and equine infectious anaemia viruses4
Virus replication2
Foot-and-mouth disease virus2
Rabies virus2
Virus structure1
PPR virus and rinderpest (history of eradication)1
Capripoxviruses and lumpy skin disease virus1
Bluetongue virus1
Avian influenza virus1
Newcastle disease virus1
Infectious bursal disease virus1
Marek's disease virus1
African and classical swine fever viruses1

6 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Foot-and-mouth disease virus · medium

Sudden death in unweaned calves during a foot-and-mouth disease outbreak, with grey-white streaks in the myocardium at post-mortem, is called:

  1. Tiger heart
  2. Zebra striping
  3. Sit-fast
  4. Turkey-egg kidney
Answer and working

A. Tiger heart

Myocarditis in young animals is the main cause of death in foot-and-mouth disease and the streaked myocardium is described as tiger heart. Turkey-egg kidney belongs to classical swine fever, zebra striping to rinderpest and PPR in the large intestine, and sit-fasts to sloughed lumpy skin disease nodules.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

2 · Rabies virus · medium

Which test is the reference standard for confirming rabies in an animal?

  1. Serum neutralising antibody titre in the live animal
  2. Skin biopsy immunohistochemistry in the live animal
  3. Direct fluorescent antibody test on brain tissue
  4. Histological search for Negri bodies alone in brain sections
Answer and working

C. Direct fluorescent antibody test on brain tissue

Diagnosis is made after death on brain tissue, with the direct fluorescent antibody test as the reference, supported by the direct rapid immunohistochemical test and genome detection. Negri bodies are absent in a substantial proportion of true cases, so histology alone cannot exclude rabies, and antibody in an unvaccinated live animal is not a diagnostic test.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

3 · Avian influenza virus · medium

Which samples are standard for investigating suspected avian influenza in a live flock?

  1. Feather pulp and dander
  2. Formalin-fixed liver and spleen (for histology)
  3. Oropharyngeal (tracheal) and cloacal swabs
  4. Serum only, taken once
Answer and working

C. Oropharyngeal (tracheal) and cloacal swabs

Respiratory and cloacal swabs capture the sites of replication and shedding and suit genome detection. A single serum sample shows exposure but not current infection, feather pulp is the sample for Marek's disease virus, and formalin destroys material needed for genome detection.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

4 · Canine parvovirus and canine distemper virus · easy

Which viruses are regarded as core canine vaccines under the widely used international guidelines, in addition to rabies where it is endemic?

  1. Canine distemper virus, canine adenovirus and canine parvovirus type 2
  2. Canine influenza virus and canine adenovirus only
  3. Canine coronavirus, canine herpesvirus and Leishmania
  4. Canine parainfluenza virus, Bordetella and Leptospira
Answer and working

A. Canine distemper virus, canine adenovirus and canine parvovirus type 2

Distemper, adenovirus and parvovirus are core for every dog, with rabies core where the disease is endemic or required by law; the others are non-core and are chosen on risk. Kennel cough components are important but are not core.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

5 · Equine influenza and equine infectious anaemia viruses · medium

Equine infectious anaemia virus is transmitted mainly by:

  1. Ingestion of contaminated feed
  2. Aerosol over long distances
  3. Biological replication in Aedes and Culex mosquitoes, as for West Nile virus in horses
  4. Mechanical transfer of blood by large biting flies and by contaminated needles
Answer and working

D. Mechanical transfer of blood by large biting flies and by contaminated needles

Tabanid and stomoxys-type flies carry infected blood on their mouthparts, and shared needles, dental instruments or blood products do the same; the virus does not replicate in the insect. Aerosol and feed-borne spread are not routes for this lentivirus.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

6 · Equine influenza and equine infectious anaemia viruses · medium

The most common serious complication of equine influenza is:

  1. Secondary bacterial pneumonia
  2. Laminitis from the virus itself
  3. Immune-mediated haemolytic anaemia
  4. Acute renal failure from viral nephritis
Answer and working

A. Secondary bacterial pneumonia

Damage to the respiratory epithelium opens the way to bacterial infection, which is why rest and careful management after the fever resolves matter as much as anything. Laminitis, haemolysis and renal failure are not typical direct consequences of equine influenza.

Further reading: Standard veterinary virology texts and WOAH Terrestrial Manual disease chapters

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Read the subject

Systematic Veterinary VirologyThe full study manual, free National Veterinary ExaminationFormat, sections and how it has changed

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Systematic Veterinary Virology for other exams

ICAR AIEEA · IndiaASRB NET and ARS / SMS / STO · IndiaICAR AICE-JRF/SRF · IndiaAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandBCSE · USA / CanadaNAVLE · USA / CanadaOPSC Veterinary Assistant Surgeon · IndiaRCVS Statutory Membership Examination · UKRPSC Veterinary Officer · IndiaSAVC Registration Examination · South AfricaTNPSC Animal Husbandry & Veterinary Science, Code 396 · IndiaUPPSC Veterinary Officer · IndiaNational Practising Veterinarian Qualification Examination · ChinaVeterinarian National Examination · South KoreaNational Licensure Examination for Veterinarians · NepalVeterinarian Licensure Examination · PhilippinesENADE · Brazil

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