ICAR AICE-JRF/SRF (PhD) · India · NTA for ICAR
Original practice questions written to the published syllabus · not past papersTraditional and complementary animal medicine: ethno-veterinary practice, Ayurveda for animals, homeopathy and traditional Chinese veterinary medicine, and how to judge their evidence and regulation.
In the exams: China national exam: TCVM is 15 of 100 marks on the clinical paper; proposed MSVE revision (not yet notified) adds an Integrative Veterinary Medicine course
How our questions for ICAR AICE-JRF/SRF spread across the units of Integrative and Ethno-Veterinary Medicine. Difficulty: 4 easy, 10 medium, 6 hard.
| Evidence base for integrative therapies | 12 | |
| Documenting ethno-veterinary knowledge | 5 | |
| Regulation of integrative veterinary practice | 2 | |
| Ayurveda for animals (Mriga Ayurveda) | 1 |
Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.
In an ethnoveterinary survey, informants give 48 use reports for gastrointestinal disorders, naming 9 plant species. Using ICF = (Nur − Nt)/(Nur − 1), what is the informant consensus factor?
D. 0.83
ICF = (48 − 9)/(48 − 1) = 39/47 = 0.83. Dividing by 48 instead of 47 gives 0.81; 9/47 = 0.19 inverts the idea; (9 − 1)/(48 − 1) = 0.17 swaps the terms. A value near 1 means informants agree on few species for this category.
Further reading: Heinrich et al., Soc Sci Med 1998
Thirty informants together give 45 use reports for one plant species. Using UV = ΣUi/N, what is its use value?
B. 1.5
UV = 45/30 = 1.5. 30/45 = 0.67 inverts the ratio; 15 is the difference 45 − 30; 2.5 has no basis in the formula.
Further reading: Phillips and Gentry 1993
In a trial of a plant anthelmintic, treated lambs average 600 eggs per gram after treatment and untreated controls average 900. Using FECR = 100 × (1 − T2/C2), what is the faecal egg count reduction?
B. 33%
FECR = 100 × (1 − 600/900) = 100 × (1 − 0.667) = 33%. 67% is the ratio 600/900 itself, 50% treats the 300 difference as a share of 600, and 150% is 900/600.
Further reading: WAAVP guidelines (FECR methods)
Diarrhoea occurs in 10 of 40 calves fed a plant additive and 16 of 40 controls. What is the relative risk reduction?
A. 37.5%
Risks are 10/40 = 0.25 and 16/40 = 0.40. RR = 0.25/0.40 = 0.625, so RRR = 1 − 0.625 = 37.5%. 15% is the absolute risk reduction in percentage points, 62.5% is the relative risk itself, and 60% is 6/10.
An owner has been giving a dog garlic daily as a 'natural' flea remedy. Which problem is most likely?
C. Heinz body haemolytic anaemia from oxidative red cell damage
Allium species contain sulfur compounds that oxidise haemoglobin and red cell membranes, forming Heinz bodies and causing haemolytic anaemia; dogs and cats are especially sensitive. Oxalate nephrosis and hypericin photosensitisation belong to other plants.
Further reading: Gupta, Veterinary Toxicology
Which pair of effects is characteristic of St John's wort (Hypericum perforatum)?
D. Primary photosensitisation from hypericin, and induction of CYP3A4 and P-glycoprotein
Hypericin is a photodynamic pigment causing primary photosensitisation. In people the plant induces CYP3A4 and P-glycoprotein, lowering levels of drugs such as ciclosporin. Phylloerythrin causes hepatogenous photosensitisation after liver damage, as with Lantana.
A horse receiving a liquorice-based herbal mix is also on a loop diuretic. Which abnormality is most likely to be worsened?
B. Hypokalaemia from mineralocorticoid excess
Glycyrrhizin's metabolite inhibits 11-beta-hydroxysteroid dehydrogenase type 2, letting cortisol act on mineralocorticoid receptors; sodium is retained and potassium lost. Loop diuretics also lose potassium, so hypokalaemia is additive.
A cat develops weakness, ataxia and tremors after the owner applied undiluted tea tree oil to its coat. Why are cats particularly at risk from such oils?
A. Their capacity for glucuronide conjugation of phenolic compounds is low
Cats have low glucuronidation capacity, so phenols and many essential oil components accumulate; tea tree oil applied undiluted or in large amounts has caused weakness, ataxia and tremors. Lipid-soluble oils are well absorbed through skin.
Further reading: Gupta, Veterinary Toxicology
Plant material used in a herbal feed mix is contaminated with aflatoxin B1. Which residue appears in the milk of dairy cows fed it?
A. Aflatoxin M1
Aflatoxin B1 is hydroxylated in the liver to aflatoxin M1, which is excreted in milk and is regulated in dairy products. G2 is another parent aflatoxin, and ochratoxin A and zearalenone are different mycotoxins.
Why are pyrrolizidine alkaloid-containing plants a residue concern in food-producing animals?
B. The alkaloids pass into milk, eggs and honey and are cumulative liver toxins
Pyrrolizidine alkaloids transfer into milk, eggs and honey and cause cumulative liver damage in consumers. They are not destroyed completely in the rumen and have no general approval as feed additives.
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