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ICAR AICE-JRF/SRF Preventive Veterinary Medicine I: Bacterial, Fungal, Rickettsial and Mycoplasmal Diseases: practice questions

ICAR AICE-JRF/SRF (PhD) · India · NTA for ICAR

Original practice questions written to the published syllabus · not past papers
10worked here, free
59written to this exam in this subject
16syllabus units

What this subject covers

The bacterial and related infectious diseases of livestock and horses: clinical signs, diagnosis, treatment, prevention and control.

In the exams: ICAR AICE-JRF core group 07 (Medicine); ICAR AIEEA-PG 13; China infectious diseases 30; TNPSC Micro/VPH/Preventive Medicine 30

What ICAR AICE-JRF/SRF asks from it

ICAR AICE-JRF/SRF (PhD) — core group 07 (Medicine)

Pathogenesis in more depth (tetanospasmin mechanism, epsilon toxin, erythritol, inverse age resistance in anaplasmosis), interpretation of tuberculin and serological tests, rationale for not treating CBPP and glanders, and national control programmes.

Where the 59 questions fall

How our questions for ICAR AICE-JRF/SRF spread across the units of Preventive Veterinary Medicine I: Bacterial, Fungal, Rickettsial and Mycoplasmal Diseases. Difficulty: 17 easy, 25 medium, 17 hard.

Brucellosis7
Haemorrhagic septicaemia5
Tuberculosis5
Mycoplasmal diseases: CBPP and CCPP5
Clostridial diseases: black quarter, enterotoxaemia and tetanus4
Anthrax4
Johne's disease4
Anaplasmosis4
Caseous lymphadenitis3
Listeriosis3
Leptospirosis3
Glanders3
Actinomycosis and actinobacillosis3
Ringworm3
Mastitis2
Strangles1

10 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Caseous lymphadenitis · easy

The major virulence factor of Corynebacterium pseudotuberculosis is:

  1. Epsilon toxin
  2. Protective antigen
  3. Phospholipase D
  4. Streptolysin O
Answer and working

C. Phospholipase D

Phospholipase D is an exotoxin that increases vascular permeability and aids spread; it is the basis of CLA toxoid vaccines and serological tests. Epsilon toxin belongs to C. perfringens type D; protective antigen to B. anthracis.

2 · Clostridial diseases: black quarter, enterotoxaemia and tetanus · hard

Under the current seven-type scheme, necrotic enteritis of broiler chickens is associated with Clostridium perfringens type:

  1. A, producing only alpha toxin
  2. C, producing beta toxin
  3. F, producing enterotoxin
  4. G, producing NetB
Answer and working

D. G, producing NetB

Since the 2018 revision, strains producing NetB are type G, and these cause avian necrotic enteritis. Older texts attribute it to type A, which is the common exam trap. Type F (alpha plus enterotoxin) causes human food poisoning.

3 · Haemorrhagic septicaemia · easy

Which species is most susceptible to haemorrhagic septicaemia?

  1. Sheep
  2. Horse
  3. Pig
  4. Water buffalo
Answer and working

D. Water buffalo

Buffalo are more susceptible than cattle, and mortality in unvaccinated buffalo is very high. Sheep, pigs and horses are only occasionally affected.

4 · Leptospirosis · easy

The maintenance host for Leptospira serovar Hardjo is:

  1. Pigs
  2. Dogs
  3. Cattle
  4. Rats
Answer and working

C. Cattle

Cattle maintain Hardjo, often with chronic renal and genital infection. Pigs maintain Pomona and Bratislava, dogs Canicola, and rats Icterohaemorrhagiae and Copenhageni.

5 · Leptospirosis · easy

The reference serological test for leptospirosis is:

  1. Rose Bengal plate test
  2. Microscopic agglutination test
  3. Complement fixation test with Johnin
  4. Milk ring test
Answer and working

B. Microscopic agglutination test

The MAT uses live leptospires of a panel of serovars and is the reference test. The Rose Bengal plate test and milk ring test are for brucellosis.

6 · Brucellosis · hard

RB51 vaccine is useful in eradication programmes because it:

  1. Is killed and cannot infect people
  2. Lacks O-polysaccharide, so it induces no antibodies detected by standard serological tests
  3. Protects equally against B. ovis
  4. Is fully susceptible to rifampicin, so accidental human infection with it is always easy to treat
Answer and working

B. Lacks O-polysaccharide, so it induces no antibodies detected by standard serological tests

RB51 is a rough mutant without O-chain, so vaccinated animals remain negative on RBPT, CFT and similar tests. It is live and infectious for people and is rifampicin-resistant, which matters for treating accidental exposure.

7 · Tuberculosis · medium

The gross lesions of avian tuberculosis in chickens are found mainly in the:

  1. Liver, spleen and intestine
  2. Lungs and bronchial lymph nodes
  3. Brain and spinal cord
  4. Skin and feathers
Answer and working

A. Liver, spleen and intestine

M. avium subsp. avium spreads by the oral route and causes tubercles in the liver, spleen, intestine and bone marrow of older birds; lungs are much less affected than in bovine TB.

8 · Glanders · hard

Regarding glanders, which is correct?

  1. Horses are fully resistant and never carry the infection
  2. Birds are usually the main reservoir
  3. The organism survives for decades in soil like anthrax spores, so pastures stay infective long after an outbreak
  4. Donkeys and mules tend to develop acute disease, while horses often become chronically infected carriers
Answer and working

D. Donkeys and mules tend to develop acute disease, while horses often become chronically infected carriers

Donkeys and mules usually die of acute disease; horses more often have chronic infection and are the long-term carriers. B. mallei is an obligate mammalian pathogen that survives only briefly in the environment.

9 · Anaplasmosis · hard

Which statement about live Anaplasma centrale vaccine is correct?

  1. It is a killed vaccine made from tick salivary glands
  2. It can prevent infection with A. marginale completely
  3. Used in Australia, South Africa, Israel and South America, it can carry other blood-borne agents and cause reactions in adults
  4. It is used worldwide, including routinely in the United States, where it is the standard licensed anaplasmosis vaccine for cattle
Answer and working

C. Used in Australia, South Africa, Israel and South America, it can carry other blood-borne agents and cause reactions in adults

A. centrale blood vaccines give protection against severe disease, not infection, and being blood-derived they risk carrying other pathogens; reactions are more likely in older cattle. They are not permitted in many countries, including the United States.

10 · Anaplasmosis · medium

Anaplasma phagocytophilum causes which condition in sheep?

  1. Heartwater
  2. Redwater
  3. Tick-borne fever
  4. Louping ill
Answer and working

C. Tick-borne fever

A. phagocytophilum infects granulocytes and causes tick-borne fever in sheep and cattle, with immunosuppression. Heartwater is Ehrlichia ruminantium; redwater is babesiosis; louping ill is viral.

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Read the subject

Preventive Veterinary Medicine I: Bacterial, Fungal, Rickettsial and Mycoplasmal DiseasesThe full study manual, free ICAR AICE-JRF/SRFFormat, sections and how it has changed

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Preventive Veterinary Medicine I: Bacterial, Fungal, Rickettsial and Mycoplasmal Diseases for other exams

ICAR AIEEA · IndiaBCSE · USA / CanadaNAVLE · USA / CanadaENADE · BrazilNational Veterinary Examination · JapanRCVS Statutory Membership Examination · UKAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New Zealand

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