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TNPSC Animal Husbandry & Veterinary Science, Code 396 Special Pathology, Necropsy & Clinical Pathology: practice questions

TNPSC Animal Husbandry & Veterinary Science (Degree Standard), Code 396 · India · Tamil Nadu Public Service Commission

Original practice questions written to the published syllabus · not past papers
10worked here, free
33written to this exam in this subject
11syllabus units

What this subject covers

The lesions of specific infectious diseases and poisonings, how to perform a post-mortem and dispatch samples, and the basics of clinical pathology.

In the exams: ICAR AICE-JRF core group 06; ICAR AIEEA-PG 13 (Pathology); ECFVG / NEB CPE necropsy section

Where the 33 questions fall

How our questions for TNPSC Animal Husbandry & Veterinary Science, Code 396 spread across the units of Special Pathology, Necropsy & Clinical Pathology. Difficulty: 20 easy, 12 medium, 1 hard.

Post-mortem technique4
Collection and dispatch of samples4
Pathology of bacterial diseases4
Pathology of viral diseases3
Pathology of toxicoses3
Clinical haematology3
Diseases of laboratory animals3
Diseases of wild animals3
Histopathology2
Cytology2
Urinalysis2

10 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Post-mortem technique · medium

Green-black discoloration of the intestinal serosa in a carcass examined two days after death in hot weather is most likely:

  1. Bile imbibition
  2. Haemosiderosis from old haemorrhage
  3. Pseudomelanosis from iron sulphide
  4. Melanosis from melanin pigment
Answer and working

C. Pseudomelanosis from iron sulphide

Pseudomelanosis forms when hydrogen sulphide from bacterial putrefaction reacts with iron from haemoglobin. True melanosis is a congenital pigment deposit, not a post-mortem change. Bile imbibition is yellow-green and confined to tissue next to the gall bladder.

Further reading: King JM et al., The Necropsy Book

2 · Collection and dispatch of samples · easy

Samples for toxicological analysis should be sent:

  1. At room temperature with added sodium azide
  2. In 10% formalin
  3. Frozen in separate clean containers without preservative
  4. Pooled together in one container with 50% glycerol saline to keep them moist
Answer and working

C. Frozen in separate clean containers without preservative

Preservatives interfere with analysis and pooling allows cross-contamination. Freezing stops decomposition of many toxins; whole blood is refrigerated rather than frozen.

Further reading: WOAH Terrestrial Manual; King JM et al., The Necropsy Book

3 · Pathology of bacterial diseases · easy

A well-fed 14-month-old bullock dies suddenly. The thigh muscle is swollen, crepitant, dark red-black and dry and spongy on cut surface, with a rancid butter odour. The most likely cause is:

  1. Clostridium chauvoei
  2. Clostridium perfringens type D
  3. Pasteurella multocida B:2
  4. Bacillus anthracis
Answer and working

A. Clostridium chauvoei

This is blackquarter: crepitant emphysematous myositis in young, well-grown cattle. Anthrax gives unclotted blood and splenomegaly without crepitant muscle; HS gives throat and brisket oedema; type D causes enterotoxaemia in sheep and goats.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.; Jubb, Kennedy and Palmer's Pathology of Domestic Animals, 6th ed.

4 · Pathology of bacterial diseases · hard

Nodules and ulcers on the nasal septum that heal as star-shaped scars in a horse are characteristic of:

  1. Equine influenza
  2. Epizootic lymphangitis
  3. Strangles
  4. Glanders
Answer and working

D. Glanders

Burkholderia mallei produces nasal ulcers that heal as stellate scars, with 'farcy buds' along skin lymphatics. Strangles produces lymph node abscesses. Epizootic lymphangitis (Histoplasma capsulatum var. farciminosum) affects skin lymphatics but not typically the nasal septum in this way.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.; Jubb, Kennedy and Palmer's Pathology of Domestic Animals, 6th ed.

5 · Pathology of viral diseases · easy

'Tiger heart' seen at necropsy of young calves or lambs is associated with:

  1. Rinderpest
  2. Rabies
  3. Bluetongue
  4. Foot-and-mouth disease
Answer and working

D. Foot-and-mouth disease

In young animals the FMD virus causes myocardial necrosis visible as pale grey-yellow streaks. Bluetongue produces haemorrhage in the pulmonary artery wall, not tiger striping.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.; Jubb, Kennedy and Palmer's Pathology of Domestic Animals, 6th ed.

6 · Clinical haematology · easy

Small dense dots at the margin of bovine red cells on a Giemsa-stained smear are most consistent with:

  1. Heinz bodies
  2. Anaplasma marginale
  3. Theileria annulata schizonts
  4. Babesia bigemina
Answer and working

B. Anaplasma marginale

A. marginale sits at the red cell margin. Babesia bigemina forms paired pear-shaped piroplasms, and Heinz bodies are denatured haemoglobin seen with new methylene blue.

Further reading: Weiss DJ, Wardrop KJ, Schalm's Veterinary Hematology, 6th ed.

7 · Clinical haematology · medium

A stress (corticosteroid) leukogram in a dog typically shows:

  1. Mature neutrophilia, lymphopenia, eosinopenia and monocytosis
  2. Neutrophilia with lymphocytosis
  3. Neutropenia with a degenerative left shift and toxic change in neutrophils
  4. Eosinophilia and basophilia
Answer and working

A. Mature neutrophilia, lymphopenia, eosinopenia and monocytosis

Corticosteroids release mature neutrophils, redistribute lymphocytes and eosinophils, and in dogs raise monocytes. Neutrophilia with lymphocytosis is the adrenaline (physiological) response seen in excited cats and horses.

Further reading: Weiss DJ, Wardrop KJ, Schalm's Veterinary Hematology, 6th ed.

8 · Cytology · medium

Vaginal cytology from a bitch shows nearly all epithelial cells as superficial, cornified cells with no neutrophils. This indicates:

  1. Early dioestrus
  2. Oestrus
  3. Anoestrus
  4. Pyometra
Answer and working

B. Oestrus

Cornification peaks in oestrus. At the onset of dioestrus, intermediate and parabasal cells and neutrophils return abruptly; anoestrus shows mainly parabasal and intermediate cells.

Further reading: Raskin RE, Meyer DJ, Canine and Feline Cytology, 3rd ed.

9 · Diseases of laboratory animals · easy

Dilated bile ducts with hyperplastic epithelium full of coccidial oocysts in a rabbit liver indicate infection with:

  1. Toxoplasma gondii
  2. Cryptosporidium parvum
  3. Eimeria tenella
  4. Eimeria stiedae
Answer and working

D. Eimeria stiedae

E. stiedae is the hepatic coccidium of rabbits. E. tenella is a caecal coccidium of chickens.

Further reading: Fox JG et al., Laboratory Animal Medicine, 3rd ed.

10 · Diseases of laboratory animals · medium

Chronic respiratory disease of laboratory rats with bronchiectasis and lung abscesses is most commonly caused by:

  1. Rat coronavirus (sialodacryoadenitis virus)
  2. Sendai virus alone
  3. Streptobacillus moniliformis
  4. Mycoplasma pulmonis
Answer and working

D. Mycoplasma pulmonis

Murine respiratory mycoplasmosis causes rhinitis, otitis media and chronic bronchopneumonia with bronchiectasis. Viruses such as Sendai may worsen it. S. moniliformis is carried by rats and causes rat-bite fever in people.

Further reading: Fox JG et al., Laboratory Animal Medicine, 3rd ed.

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Read the subject

Special Pathology, Necropsy & Clinical PathologyThe full study manual, free TNPSC Animal Husbandry & Veterinary Science, Code 396Format, sections and how it has changed

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Special Pathology, Necropsy & Clinical Pathology for other exams

ASRB NET and ARS / SMS / STO · IndiaRPSC Veterinary Officer · IndiaAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandBCSE · USA / CanadaENADE · BrazilNational Veterinary Examination · JapanNAVLE · USA / CanadaPAVE and its QSE · USARCVS Statutory Membership Examination · UK

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