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TNPSC Animal Husbandry & Veterinary Science, Code 396 Systemic Veterinary Pathology: practice questions

TNPSC Animal Husbandry & Veterinary Science (Degree Standard), Code 396 · India · Tamil Nadu Public Service Commission

Original practice questions written to the published syllabus · not past papers
9worked here, free
20written to this exam in this subject
12syllabus units

What this subject covers

Lesions organ system by organ system, plus the pathology of nutritional and production diseases.

In the exams: ICAR AICE-JRF core group 06; ICAR AIEEA-PG 13 (Pathology)

Where the 20 questions fall

How our questions for TNPSC Animal Husbandry & Veterinary Science, Code 396 spread across the units of Systemic Veterinary Pathology. Difficulty: 13 easy, 7 medium, 0 hard.

Pathology of the gastrointestinal tract2
Pathology of the urinary system2
Pathology of the nervous system2
Pathology of the musculoskeletal system2
Pathology of the reproductive system2
Pathology of the endocrine system2
Nutritional pathology2
Production pathology2
Pathology of the cardiovascular system1
Pathology of the respiratory system1
Pathology of the liver1
Pathology of the skin1

9 practice questions, worked

Choose an answer, then open the working. Each explanation says why the right answer is right and why the others are not.

1 · Pathology of the cardiovascular system · easy

The term 'nutmeg liver' describes which lesion?

  1. Chronic passive congestion of the liver from right-sided heart failure
  2. Diffuse hepatic lipidosis from negative energy balance in late pregnancy
  3. Multifocal hepatic necrosis from bacteraemia
  4. Biliary cirrhosis from chronic fasciolosis
Answer and working

A. Chronic passive congestion of the liver from right-sided heart failure

Right-sided failure raises central venous pressure, so centrilobular sinusoids stay congested (dark) while periportal tissue is pale or fatty, giving a nutmeg pattern on the cut surface. Lipidosis makes the whole liver uniformly yellow and greasy, not mottled in a lobular pattern.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

2 · Pathology of the respiratory system · easy

The most common distribution of bronchopneumonia in domestic animals is:

  1. Cranioventral
  2. Caudodorsal lobes
  3. Diffuse throughout all lobes
  4. Random multifocal
Answer and working

A. Cranioventral

Inhaled organisms settle in the cranioventral lobes, so bronchopneumonia starts there. Diffuse lesions suggest interstitial pneumonia and random multifocal lesions suggest embolic pneumonia; caudodorsal lesions suggest lungworm or porcine pleuropneumonia.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

3 · Pathology of the gastrointestinal tract · easy

Wooden tongue in cattle is caused by:

  1. Actinomyces bovis
  2. Fusobacterium necrophorum
  3. Actinobacillus lignieresii
  4. Dermatophilus congolensis
Answer and working

C. Actinobacillus lignieresii

Actinobacillus lignieresii causes pyogranulomatous inflammation of soft tissue, notably the tongue. Actinomyces bovis causes lumpy jaw, an osteomyelitis of the mandible; the two are often confused.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

4 · Pathology of the gastrointestinal tract · medium

A sharp 'bloat line' in the cervical oesophagus at necropsy of a cow indicates:

  1. Post-mortem gas accumulation only (autolysis)
  2. Oesophageal obstruction by a foreign body
  3. Ante-mortem ruminal tympany (bloat)
  4. Rumen acidosis without any distension
Answer and working

C. Ante-mortem ruminal tympany (bloat)

Ante-mortem bloat compresses the thoracic oesophagus and veins, leaving the cervical part congested and the thoracic part pale with a sharp junction. Post-mortem gas forms after circulation stops, so it cannot create this congestion boundary.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

5 · Pathology of the urinary system · medium

Enzootic bovine haematuria, with haemorrhagic cystitis and urinary bladder tumours, is associated with prolonged ingestion of:

  1. Bracken fern (Pteridium)
  2. Oak leaves and acorns (Quercus)
  3. Lantana camara
  4. Oxalate-rich grasses
Answer and working

A. Bracken fern (Pteridium)

Ptaquiloside in bracken fern is a carcinogen that causes bladder haemorrhage and tumours after long-term grazing; bovine papillomavirus may act with it. Oak causes acute tubular nephrosis and Lantana causes hepatogenous photosensitisation.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

6 · Pathology of the nervous system · medium

Hansen type I intervertebral disc disease occurs typically in:

  1. Old non-chondrodystrophic large breeds only, such as the German shepherd
  2. Chondrodystrophic breeds such as the dachshund
  3. Young horses with wobbler syndrome
  4. Cattle with copper deficiency
Answer and working

B. Chondrodystrophic breeds such as the dachshund

Type I is acute extrusion of a degenerated, often mineralised nucleus pulposus in chondrodystrophic breeds. Type II, a slow protrusion of the annulus, is typical of older non-chondrodystrophic dogs.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

7 · Pathology of the reproductive system · easy

A freemartin is a sterile heifer born twin to a bull because of:

  1. Maternal oestrogen excess
  2. Iodine deficiency during pregnancy
  3. Placental vascular anastomoses causing XX/XY chimerism
  4. Infection of the dam with Campylobacter fetus in early gestation
Answer and working

C. Placental vascular anastomoses causing XX/XY chimerism

Fusion of placental circulations allows exchange of cells and hormones, so the female twin becomes a chimera with masculinised, hypoplastic reproductive organs. Campylobacter fetus causes infertility and early embryonic death, not freemartinism.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

8 · Pathology of the endocrine system · easy

The most common cause of spontaneous hyperadrenocorticism in dogs is:

  1. A functional pituitary corticotroph adenoma or hyperplasia (pituitary-dependent)
  2. A functional adrenocortical carcinoma or adenoma secreting cortisol (adrenal-dependent) independently of ACTH
  3. Phaeochromocytoma
  4. Immune-mediated adrenalitis
Answer and working

A. A functional pituitary corticotroph adenoma or hyperplasia (pituitary-dependent)

About 80-85% of canine Cushing's syndrome is pituitary-dependent, with both adrenal cortices hyperplastic from ACTH excess. Adrenal tumours account for the rest; immune-mediated adrenalitis causes the opposite disease, hypoadrenocorticism.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

9 · Production pathology · medium

Pale, soft, exudative (PSE) pork is associated with:

  1. Depletion of muscle glycogen by chronic stress before slaughter, giving an abnormally high final muscle pH
  2. Vitamin E deficiency in finishing pigs
  3. Rapid post-mortem glycolysis in stress-susceptible pigs, dropping muscle pH while the carcass is warm
  4. Excess dietary copper
Answer and working

C. Rapid post-mortem glycolysis in stress-susceptible pigs, dropping muscle pH while the carcass is warm

In pigs with the RYR1 mutation or acute pre-slaughter stress, lactic acid accumulates quickly while the carcass is warm, denaturing proteins so meat is pale, soft and watery. Chronic stress depletes glycogen and gives the opposite, dark, firm, dry (DFD) meat.

Further reading: Zachary JF, Pathologic Basis of Veterinary Disease, 7th ed.

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Read the subject

Systemic Veterinary PathologyThe full study manual, free TNPSC Animal Husbandry & Veterinary Science, Code 396Format, sections and how it has changed

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Systemic Veterinary Pathology for other exams

ASRB NET and ARS / SMS / STO · IndiaENADE · BrazilNational Veterinary Examination · JapanRPSC Veterinary Officer · IndiaAustralasian Veterinary Examination, formerly the National Veterinary Examination · Australia / New ZealandBCSE · USA / CanadaNAVLE · USA / CanadaPAVE and its QSE · USARCVS Statutory Membership Examination · UK

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