ICAR AIEEA Rotating Internship & Entrepreneurship Training: practice questions

Question 1 · medium

Why must an oil-adjuvanted inactivated vaccine never be frozen?

1. Freezing activates the killed organisms, turning them into live vaccine
2. Freezing is harmless, but frozen vials are hard to fit into syringes
3. Freezing breaks the adjuvant emulsion and reduces the vaccine's potency
4. Freezing increases the antigen content and causes overdosing in animals

Question 2 · medium

What is the purpose of the seed-lot system in vaccine production?

1. Every batch is tested only after it is sold, using reports from the field veterinarians
2. Every batch uses whatever field isolate is most recent, so the vaccine matches current strains
3. Every batch starts from a defined master or working seed of known identity and passage level
4. Every batch is grown in a different substrate so that no two batches are ever identical

Question 3 · hard

Which set of tests forms the basic batch quality control of an inactivated bacterial vaccine before release?

1. Sterility, safety, potency and complete inactivation
2. Gram stain, motility, catalase and oxidase of the final product
3. Fat, solids-not-fat, acidity and the clot-on-boiling stability
4. Crude protein, crude fibre, ether extract and total ash content

Question 4 · medium

Why does a vaccine institute keep detailed records of each batch's production and testing?

1. So that field veterinarians can choose a batch by the name of its technician
2. So that the batch can be relabelled with a later expiry date if it is unsold
3. So that any adverse event or failure in the field can be traced to its batch
4. So that records replace the need to store retained samples of the batch

Question 5 · easy

In a live attenuated vaccine, what has been done to the organism?

1. Its virulence has been reduced while it can still replicate in the host
2. It has been killed by formalin treatment so it can no longer replicate at all
3. It has been split into purified proteins with no genetic material
4. Only its toxin has been inactivated to make a toxoid for injection

Question 6 · easy

Which component of Weende proximate analysis is calculated by difference rather than measured directly?

1. Nitrogen-free extract
2. Ether extract
3. Crude protein
4. Total ash

Question 7 · easy

In India, which schedule of the Drugs and Cosmetics Rules sets out good manufacturing practice for pharmaceutical products?

1. Schedule H
2. Schedule C
3. Schedule X
4. Schedule M

Question 8 · medium

In a feed mill, mixing uniformity matters most for which ingredients?

1. The bagging material, because it touches every kilogram of the feed
2. The main energy grain, because it forms the bulk of the ration by weight and volume
3. Micro-ingredients such as vitamins, trace minerals and approved additives
4. Water added at pelleting, because it evaporates during the cooling stage

Question 9 · easy

In an IMRaD-format project report, which section presents the findings without interpreting them?

1. Results
2. Introduction
3. Discussion
4. Abstract

Question 10 · medium

Which of the following is research misconduct in an internship project report?

1. Listing the small sample size as a limitation of the study in the report
2. Replacing three inconvenient values with numbers that fit the expected result
3. Citing a published paper whose methods were used for the sampling design
4. Reporting a non-significant result honestly in the discussion of the findings